Медицина - скачать книги или читать онлайн. Страница 146

Preterm birth is a major challenge in perinatal health care. Most perinatal deaths occur in preterm infants, and preterm birth is an important risk factor for neurological damage, including cerebral palsy. This ABC covers all the latest information on this complex and multidisciplinary area from obstetric issues to immediate care of preterm infants, respiratory complications, and how to provide support to the parents and relatives of the preterm infant. With its clear explanation and many illustrations, general practitioners, medical students, paediatricians starting their postgraduate training, nurses, and midwives will find ABC of Preterm Birth an excellent reference.

Prehospital care is a growing area in medicine, and emergency treatments are becoming more sophisticated as the potential to save lives grow. The fourth edition of this ABC has been thoroughly updated and includes new chapters on nuclear and biological emergencies. Each chapter gives concise and clear guidance and is accompanied by excellent photographs and diagrams. Edited and written by leading UK trauma authorities, this is a truly comprehensive and practical book for everyday use by emergency medicine staff, nurses, hospital doctors, paramedics, and ambulance services. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

This new edition of Surgery at a Glance provides a concise and visually-orientated summary of a comprehensive lecture course in surgery. Following the easy-to-use at a Glance format, each topic is presented with clear illustrations and key facts encapsulating all that you need to know. The book is coherently divided into clinical presentations followed by major surgical conditions. Exploring core principals and important diseases, it is an accessible companion to any surgery core text, and is ideally placed to support the current curriculum. Surgery at a Glance: • Features brand new chapters on Orthopaedics and updates on the management of surgical conditions • Includes more revision-friendly elements for quick reference • Is fully supported by a resource website at www.testgeneralsurgery.com containing both MCQs and short answer questions

This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice ‘Hot topics’ boxes that focus on the latest developments in testing, assessment and treatment ‘Ethical issues’ boxes to prompt further thought and discussion on the implications of genetic developments ‘Sources of information’ boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Clinical Pharmacology and Therapeutics Lecture Notes provides a clear and accessible overview of all the key prescribing topics needed for medical finals and beyond. Detailed coverage and discussion of pharmacology in a clinical context, combined with an easy-to-understand, readable style, helps improve and test understanding of pharmacological principles and reasoning on rotation and into the foundation years. Key features for this edition include: • Clinical scenarios to root each chapter firmly in a real-life setting • Prescribing points flagging up important issues of clinical relevance • Expanded sections on drugs you may need in a hurry, prescribing and its pitfalls, and paediatric prescribing • A self-assessment section to test your knowledge and help prepare for examinations Clinical Pharmacology and Therapeutics Lecture Notes is an ideal resource for all medical students, junior doctors, and other prescribers, whether learning how pharmacological principles relate to clinical situations, brushing up on the basics while on rotation, or looking for a comprehensive overview of prescribing and therapeutics.

Successful management of eye disease relies on the veterinarian’s ability to identify ocular features and distinguish pathologic changes. Atlas of Feline Ophthalmology, Second Edition is an invaluable diagnostic reference, providing high-quality color photographs for comparison with a presenting complaint. Presenting 394 photographs illustrating both normal and pathologic ocular conditions, this Second Edition offers a current, complete reference on ocular diseases, adding conditions recognized since publication of the first edition, a broader geographic scope, and many new images with improved quality. Carefully designed for easy reference, the contents are divided into sections corresponding to specific anatomical structures of the eye. A useful appendix new to this edition groups figures by etiology, making it easy to find every image associated with a specific agent or disease. Atlas of Feline Ophthalmology, Second Edition is a useful tool aiding general practitioners in diagnosing eye disease in cats.

The American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an «unparalleled collection of knowledge.» Since the first edition's publication, advances have been made in diagnosis, understanding, and treatment of genetic syndromes, resulting in the potential for a higher quality of life for individuals affected. Management of Genetic Syndromes, Second Edition incorporates all the most recent developments in knowledge about and management of the most common genetic syndromes seen in children and adults. Expanded to cover twenty-five new syndromes, this comprehensive new edition also features thorough updates of chapters from the first edition. Edited by two of the field's most highly esteemed experts, each chapter is written by an expert with extensive direct professional experience with that disorder and includes detailed coverage of: Incidence Etiology and pathogenesis Natural history Diagnostic criteria and diagnostic testing, including photographs of distinctive physical findings Differential diagnosis Evaluation Management throughout life References and resources, including family support organizations Written to be clear and accessible to medical generalists and specialists, as well as allied health and education professionals and families, Management of Genetic Syndromes, Second Edition provides a unique and up-to-date resource for this rapidly developing field.

The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) – the ultimate online resource for NMR and MRI. To date there is no single reference aimed at teaching the art of applications guided coil design for use in MRI. This RF Coils for MRI handbook is intended to become this reference. Heretofore, much of the know-how of RF coil design is bottled up in various industry and academic laboratories around the world. Some of this information on coil technologies and applications techniques has been disseminated through the literature, while more of this knowledge has been withheld for competitive or proprietary advantage. Of the published works, the record of technology development is often incomplete and misleading, accurate referencing and attribution assignment being tantamount to admission of patent infringement in the commercial arena. Accordingly, the literature on RF coil design is fragmented and confusing. There are no texts and few courses offered to teach this material. Mastery of the art and science of RF coil design is perhaps best achieved through the learning that comes with a long career in the field at multiple places of employment…until now. RF Coils for MRI combines the lifetime understanding and expertise of many of the senior designers in the field into a single, practical training manual. It informs the engineer on part numbers and sources of component materials, equipment, engineering services and consulting to enable anyone with electronics bench experience to build, test and interface a coil. The handbook teaches the MR system user how to safely and successfully implement the coil for its intended application. The comprehensive articles also include information required by the scientist or physician to predict respective experiment or clinical performance of a coil for a variety of common applications. It is expected that RF Coils for MRI becomes an important resource for engineers, technicians, scientists, and physicians wanting to safely and successfully buy or build and use MR coils in the clinic or laboratory. Similarly, this guidebook provides teaching material for students, fellows and residents wanting to better understand the theory and operation of RF coils. Many of the articles have been written by the pioneers and developers of coils, arrays and probes, so this is all first hand information! The handbook serves as an expository guide for hands-on radiologists, radiographers, physicians, engineers, medical physicists, technologists, and for anyone with interests in building or selecting and using RF coils to achieve best clinical or experimental results. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fiel

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

Of all the complications which arise from diabetes, cardiovascular complications are by far the most prevalent and the most deadly. Authored by some of the world's leading names in this area, this outstanding book provides all those managing diabetic patients with clinical, practical and succinct guidance to the diagnosis and management of cardiovascular complications in diabetes. With a joint endocrinology and cardiology focus, and with the very latest in clinical guidelines from the ADA, EASD, AHA, ASC and ESC, selected highlights include: – The role of new biomarkers of cardiovascular disease in diabetes – The latest on diagnosis of cardiovascular problems via vascular imaging – Hypertension and cardiovascular disease in the diabetic patient – Dyslipidaemia and its management in type 2 diabetes – Management of thrombosis, acute coronary syndrome and peripheral arterial disease in diabetes Key points, case studies and self-assessment questions allow for rapid-reference, quick understanding of all topics, thus ensuring that this is perfect reading for endocrinologists, diabetes specialists and cardiologists of all levels managing patients with diabetes and associated cardiovascular problems.

The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent that integration, inform the drug research processes that are most relevant to the pharmaceutical and biotechnology industries. The first book to focus on comprehensive systems biology and its applications in drug discovery and development, it offers comprehensive and multidisciplinary coverage of all phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design and execution, as well as the complementary systems approaches that make these processes more efficient. It also provides models for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker identification. Introducing and explaining key methods and technical approaches to the use of comprehensive systems biology on drug development, the book addresses the challenges currently facing the pharmaceutical industry. As a result, it is essential reading for pharmaceutical and biotech scientists, pharmacologists, computational modelers, bioinformaticians, and graduate students in systems biology, pharmaceutical science, and other related fields.

Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.