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The legal implications of conducting clinical research and trials are becoming more complex. Everyone involved in clinical research increasingly needs to be aware of not only the ethical issues at stake but also how the law affects medical practice and research. Much of clinical research and trial law and litigation is comparatively recent and researchers need to ensure current compliance on a wide range of issues. Including: standards and duty of care informed consent conflicts of interest research contracts establishing clinical trials the disclosure and withholding of clinical trial results Clinical Research and the Law comprehensively discusses these topics and provides the answers to the legal questions and potential pitfalls encountered in medical research. It is an up-to-date, practical guide for clinical investigators and their institutional administrators, particularly risk managers and research administrators, as well as healthcare administrators and members of institutional review boards. This book is also a key resource for medical students, postgraduate research students, practicing attorneys and counselors for teaching hospitals and institutions undertaking clinical research and contract research organizations.

Thinking about a surgical career? About to start surgical training? Do you know what to expect and how to thrive? The Hands-on Guide to Surgical Training is the ultimate, practical guide for medical students and junior doctors thinking about taking the plunge into surgery, and also for surgical trainees already in training. It’s full of invaluable, practical information and career guidance to ensure you get the most out of your surgical career. It offers general guidance and advice on surgical training, together with detailed information on each of the nine surgical subspecialties, each written by seniors and consultants, as you make both clinical and career-based choices. Undoubtedly one of the most comprehensive resources for surgical trainees available, The Hands-on Guide to Surgical Training will be essential reading throughout your training and surgical career. Take the stress out of surgical training with The Hands-on Guide!

The thoroughly revised and updated fourth edition of Foodservice Manual for Health Care Institutions offers a review of the management and operation of health care foodservice departments. This edition of the book—which has become the standard in the field of institutional and health care foodservice—contains the most current data on the successful management of daily operations and includes information on a wide range of topics such as leadership, quality control, human resource management, product selection and purchasing, environmental issues, and financial management. This new edition also contains information on the practical operation of the foodservice department that has been greatly expanded and updated to help institutions better meet the needs of the customer and comply with the regulatory agencies'standards. TOPICS COVERED INCLUDE: Leadership and Management Skills Marketing and Revenue-Generating Services Quality Management and Improvement Planning and Decision Making Organization and Time Management Team Building Effective Communication Human Resource Management Management Information Systems Financial Management Environmental Issues and Sustainability Microbial, Chemical, and Physical Hazards HACCP, Food Regulations, Environmental Sanitation, and Pest Control Safety, Security, and Emergency Preparedness Menu Planning Product Selection Purchasing Receiving, Storage, and Inventory Control Food Production Food Distribution and Service Facility Design Equipment Selection and Maintenance Learning objectives, summary, key terms, and discussion questions included in each chapter help reinforce important topics and concepts. Forms, charts, checklists, formulas, policies, techniques, and references provide invaluable resources for operating in the ever-changing and challenging environment of the food-service industry. Companion Web site: www.josseybass.com/go/puckett4e Additional resources: www.josseybasspublichealth.com

The Built Environment and Public Health The Built Environment and Public Health explores the impact on our health of the environments we build for ourselves, and how public health and urban planning can work together to build settings that that promote healthy living. This comprehensive text covers origins and foundations of the built environment as a public health focus and its joint history with urban planning, transportation and land use, infrastructure and natural disasters, assessment tools, indoor air quality, water quality, food security, health disparities, mental health, social capital, and environmental justice. The Built Environment and Public Health explores such timely issues as: Basics of the built environment and evidence for its influences How urban planning and public health intersect How infrastructure improvements can address chronic diseases and conditions Meeting the challenges of natural disasters Policies to promote walking and mass transit Approaches to assess and improve air quality and our water supply Policies that improve food security and change how Americans get their food How the built environment can address needs of vulnerable populations Evidence-based design practices for hospitals and health care facilities Mental health, stressors, and health care environments Theories and programs to improve social capital of low-income communities How the built environment addresses issues of health equity and environmental justice This important textbook and resource includes chapter learning objectives, summaries, questions for discussion, and listings of key terms. Companion Web site: www.josseybass.com/go/lopez

A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in characterizing potential drugs and their production and synthesis, Development of Therapeutic Agents Handbook gives professionals a basic tool to facilitate research and development within this challenging process. This comprehensive text brings together, in one resource, a compendium of concepts, approaches, methodologies, and limitations that need to be considered in the formulation of therapeutic agents across a range of therapeutic fields. Both a reference and a call to action for the pharmaceutical industry, Development of Therapeutic Agents Handbook examines recent innovations taking shape in the various medical disciplines involved in drug discovery, and shows why these advances need to be embraced universally among researchers to improve their solution strategies. Additional subject matter includes: Extensive coverage and in-depth look into novel treatments and therapeutics Discussion of hot topics like new drugs and nutraceuticals, the discovery and development of vaccines, cancer therapeutics, and market overviews Coverage of therapeutic drug development for specific disease areas, such as cardiology, oncology, breast cancer, and kidney diseases As research in biology, chemistry, medicine, and technology rapidly progresses, it is becoming increasingly important for medical researchers to maintain an up-to-date knowledge base of emerging trends directing promising new therapies. Development of Therapeutic Agents Handbook serves this purpose, acting as both a one-stop reference rich in valid science, and a tool to carve out new pathways in the pursuit of bringing safer and more effective drugs to the marketplace.

A fundamental and straightforward guide to using and understanding statistical concepts in medical research Designed specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today's biomedical research and provides insight on their appropriate application. Rather than provide detailed mathematics for each of these methods, the book emphasizes what healthcare practitioners need to know to interpret and incorporate the latest biomedical research into their practices. The author draws from his own experience developing and teaching biostatistics courses for physicians and nurses, offering a presentation that is non-technical and accessible. The book begins with a basic introduction to the relationship between biostatistics and medical research, asking the question «why study statistics?,» while also exploring the significance of statisitcal methods in medical literature and clinical trials research. Subsequent chapters explore key topics, including: Correlation, regression, and logistic regression Diagnostics Estimating means and proportions Normal distribution and the central limit theorem Sampling from populations Contingency tables Meta-analysis Nonparametric methods Survival analysis Throughout the book, statistical methods that are often utilized in biomedical research are outlined, including repeated measures analysis of variance, hazard ratios, contingency tables, log rank tests, bioequivalence, cross-over designs, selection bias, and group sequential methods. Exercise sets at the end of each chapter allow readers to test their comprehension of the presented concepts and techniques. The Essentials of Biostatistics for Physicians, Nurses, and Clinicians is an excellent reference for doctors, nurses, and other practicing clinicians in the fields of medicine, public health, pharmacy, and the life sciences who need to understand and apply statistical methods in their everyday work. It also serves as a suitable supplement for courses on biostatistics at the upper-undergraduate and graduate levels.

Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes, industries need to review and streamline their manufacturing processes. This two volume handbook systematically addresses the key steps and challenges in the production process and provides valuable information for medium to large scale producers of biopharmaceuticals. It is divided into seven major parts: – Upstream Technologies – Protein Recovery – Advances in Process Development – Analytical Technologies – Quality Control – Process Design and Management – Changing Face of Processing With contributions by around 40 experts from academia as well as small and large biopharmaceutical companies, this unique handbook is full of first-hand knowledge on how to produce biopharmaceuticals in a cost-effective and quality-controlled manner.

Sedation is a procedure that makes use of sedative medications to produce a relaxed experience for the patient. The central nervous system (CNS) is affected through the use of drugs, including tranquilizers and anxiolytics, that can be administered to the patient in several ways. Sedation dentistry has several benefits, both for dentists and patients. For patients, it can mean freedom from anxiety or fear during dental procedures. In cases where a patient has not been able to undergo dental treatment for many years because of this fear, sedation dentistry allows him to have several years' worth of dental treatment in just a few sessions. For dentists, sedation dentistry facilitates the easy performance of dental procedures. Patients are likely to be more cooperative under the relaxing effects of sedation. Treatments can also be quicker, because a number of procedures can be performed in a single session. Dental nurses play a vital role in assisting the dentist in the routine sedation of patients. In acknowledgement of this, the NEBDN run a post-qualification certificate in Dental Sedation Nursing that provides the dental nurse with the theoretical knowledge and practical skills required to carry out their role safely and competently. The ‘Basic Guide to Dental Sedation Nursing' is a must have book for all dental nurses seeking to develop their knowledge and understanding of this core area of clinical practice. Written in a clear and accessible style, chapters reflect the Certificate in Dental Sedation Nursing syllabus with chapters on such key topics as legal aspects, anatomy, equipment, patient assessment, types of sedation, medical emergencies and resuscitation. Illustrated in full colour throughout Handy format for easy reference and portability Evidence-based

Current Best Practice in Interventional Cardiology addresses the questions which challenge clinicians involved with interventional procedures. Helpfully organized into four sections, the text addresses; coronary artery disease, non-coronary interventions, left ventricular failure and the latest advances in imaging technologies, and provides authoritative guidance on the current recommendations for best practice. Containing contributions from an international team of opinion leaders, this new book reviews the key advances in equipment, techniques and therapeutics and is an accessible reference for all hospital-based specialists.

Assessment and monitoring are fundamental aspects of the care of the acutely ill child, especially in high dependency areas and critical care units. Clinical Assessment and Monitoring in Children is a practical, introductory guide which provides detailed information on assessment and monitoring techniques, including physical assessment, physiological monitoring and an appraisal of additional assessment tools to enable practitioners to develop effective skills. The book adopts a physical systems approach, discusses assessment strategies and tools (starting with the least invasive and moving to the more complex) and examines how to analyse and apply the information to provide ongoing care. Each chapter explores physical assessment and examination whilst maintaining the focus on the child and the family. Clinical Assessment and Monitoring in Children assumes no prior knowledge, and provides the knowledge and skills needed to underpin decision-making and provide effective evidence-based care. This is an invaluable resource for all health care practitioners involved in caring for children. Key Features: • Explores assessment and monitoring of children from 0 – 16 years • Draws upon National Service Frameworks and clinical practice guidelines • Adopts a system by system approach • Provides knowledge and skills needed to underpin decision-making and provide effective evidence-based care • Includes hints on trouble-shooting and gaining the child and family’s co-operation • Includes case studies and suggested further reading

Society-sanctioned guidelines on care are valuable tools, but accessing key information from the often complicated statements has been a daunting task. Now, practitioners and their institutions have a clear path to successful application of guidelines from the American Heart Association. This book outlines the key AHA guidelines, Statements, and Performance Measures and includes comparisons with the associated European guidelines. This book also has a strong online component, which will alert users who sign up to new updates to the guidelines and other relevant information. It will also have links through to the full guidelines and statements.

This book in the new American Heart Association Clinical Series, explores and explains state-of-the-art use of antiplatelet agents and draws on the expertise of global leaders in antiplatelet therapy. Skillfully organized for fast reference, the book is divided into five parts: Concepts in Platelet Physiology, Function, and Measurement Pharmacology of Oral Antiplatelet Agents Pharmacology of Intravenous Antiplatelet Agents Clinical Use of Antiplatelet Agents in Cardiovascular Disease Special Circumstances. Each chapter in the clinical section contains an overview of guidelines, plus specifics on medical and interventional uses. Clinical cardiologists, platelet biologists, and a wide range of practicing and prospective clinicians in allied fields will find this text an exceptional source of current information.