Медицина - скачать книги или читать онлайн. Страница 185

Covering cases from Addison's disease to osteoporosis and diabetic foot ulcer, and an introductory section explaining the molecular and physiological aspects of endocrinology, Endocrinology and Diabetes: Clinical Cases Uncovered has it all. Reflecting the varied nature of the specialty, the cases cover various endocrine conditions and address the clinical presentation, diagnostic workup and potential complications, while the self-assessment section, comprising 30 MCQ, 10 SAQs and 10 EMQs, will help medical students, junior doctors, and nurses practise clinical reasoning and prepare for life on the wards.

Written by authorities from various related specialties, this book presents the most complete treatment possible of the conditions responsible for water- and sanitation-related diseases, the pathogens and their biology, morbidity and mortality resulting from lack of safe water and sanitation, distribution of these diseases, and the conditions that must be met to reduce or eradicate them. Preventive measures and solutions are presented throughout. This book is an essential resource for all graduate students, postdoctoral scholars, and professionals in infectious disease, public health and medicine, chemical and environmental engineering, and international affairs. Key features: Provides a comprehensive understanding of the interconnection among many factors related to water-related diseases, sanitation and hygiene Brings together experts from various specialties to address each area covered and to assist in bringing about the understanding of those interconnections Provides examples of successful interventions with knowledge about how they were brought about so that information can be use to replicate the initiative in full or in part Provides an appreciation of the concerns and solutions addressed from an international perspective with high and low technological solutions Provides insight into the international dimension of these concerns and how they can be best addressed Four hours of accompanying multimedia DVD on two discs Learn more about this title and share information with colleagues and friends using this three-page flier: http://www.solutions-site.org/dvd/insert.pdf

This textbook is a clear and accessible introduction to the scientific and clinical aspects of the creation, development and administration of drugs or drug regimens used in the treatment of cancer. Unique in its approach, this book enables the student to gain an understanding of the pathological, physiological and molecular processes governing malignancy, whilst also introducing the role of health professionals and scientists in the research and treatment of cancer. The book consolidates all the essential information necessary for a full understanding of cancer chemotherapy, providing an informative, inexpensive and up-to-date coverage of the subject aimed at an undergraduate level readership. Key Features: Incorporates numerous diagrams, tables and illustrations to aid understanding. Examines key pharmacological and pharmaceutical issues such as dosing, toxicity and preparation of anti-cancer drugs. Includes a key chapter of practice essay questions to ease revision. Comprehensive coverage of drugs currently in pre-clinical and clinical development. An indispensable text for undergraduate students studying pharmacy and medicine as well as those doing courses such as molecular biology, biomedical sciences and pharmacology which cover aspects of oncology.

This book explains the ecology of viruses by examining their interactive dynamics with their hosting species (in this volume, in animals), including the types of transmission cycles that viruses have evolved encompassing principal and alternate hosts, vehicles and vectoring species. Examining virology from an organismal biology approach and focusing on the concept that viral infections represent areas of overlap in the ecologies of the involved species, Viral Ecology is essential for students and professionals who either may be non-virologists or virologists whose previous familiarity has been very specialized.

This book provides a practical guide to analysis of simple and complex method comparison data, using Stata, SAS and R. It takes the classical Limits of Agreement as a starting point, and presents it in a proper statistical framework. The model serves as a reference for reporting sources of variation and for providing conversion equations and plots between methods for practical use, including prediction uncertainty. Presents a modeling framework for analysis of data and reporting of results from comparing measurements from different clinical centers and/or different methods. Provides the practical tools for analyzing method comparison studies along with guidance on what to report and how to plan comparison studies and advice on appropriate software. Illustrated throughout with computer examples in R. Supported by a supplementary website hosting an R-package that performs the major part of the analyses needed in the area. Examples in SAS and Stata for the most common situations are also provided. Written by an acknowledged expert on the subject, with a long standing experience as a biostatistician in a clinical environment and a track record of delivering training on the subject. Biostatisticians, clinicians, medical researchers and practitioners involved in research and analysis of measurement methods and laboratory investigations will benefit from this book. Students of statistics, biostatistics, and the chemical sciences will also find this book useful.

Pharmacovigilance Medical Writing covers the preparation of pharmacovigilance documents for all stages of the drug development process (i.e. from clinical development through to applications for marketing authorisations to the post-marketing stage). For each document, the book presents a review of the regulatory framework that governs the content of the document, followed by practical guidance (e.g. scheduling, source data, department/functions involved in document preparation/review, appropriate timelines and planning activities), ending with a generic model document compliant with the current guidelines, which can be modified to meet specific company and product requirements.

To the dentist or maxillofacial practitioner, radiology is an essential diagnostic discipline and a valuable tool for treatment planning. Now more than ever, dentists are often the first to encounter lesions of the face and jaws and are frequently held liable for recognizing pathologies and other sites of concern. Oral and Maxillofacial Radiology: A Diagnostic Approach provides clinicians of varied disciplines and skill levels a practical and systematic approach to diagnosing lesions affecting the face and jaws. Firmly grounded in evidence-based research, the book presents a clear understanding of the clinical impact of each lesion within a prospective diagnosis. Oral and Maxillofacial Radiology is logically organized, beginning with the basics of radiological diagnosis before discussing each of the advanced imaging modalities in turn. Modalities discussed include helical and cone-beam computed tomography, magnetic resonance imaging, positron emission tomography, and ultrasonography. Later chapters cover radiological pathologies of the jaw, and also those of the head and neck immediately outside the oral and maxillofacial region. Written by a recognized expert in the field, Oral and Maxillofacial Radiology contains a multitude of clinical images, practical examples, and flowcharts to facilitate differential diagnosis.

This cutting-edge title is one of the first devoted entirely to the issue of carbofuran and wildlife mortality. It features a compilation of international contributions from policy-makers, researchers, conservationists and forensic practitioners and provides a summary of the history and mode of action of carbofuran, and its current global use. It covers wildlife mortality stemming from legal and illegal uses to this point, outlines wildlife rehabilitation, forensic and conservation approaches, and discuss global trends in responding to the wildlife mortality. The subject of carbofuran is very timely because of recent parallel discussions to withdraw and reinstate the insecticide in different parts of the world. Incidences of intentional and unintentional wildlife poisonings using carbofuran are undeniably on the rise, especially in Africa and India and gatherings of stakeholders are being organized and convened on a global basis. There is still a need to consolidate information on the different experiences and approaches taken by stakeholders. Carbofuran and Wildlife Poisoning is a comprehensive overview of global wildlife mortality, forensic developments and monitoring techniques and is a definitive reference on the subject. It comprises of historical and current perspectives, contributions from key stakeholders in the issue of global wildlife poisonings with carbofuran, people on the ground who deal with the immediate and long-term ramifications to wildlife, those who have proposed or are working towards mitigative measures and solutions, those in contact with intentional or unintentional 'offenders', those who have adapted and developed forensic methodology and are gathering evidence. «Carbofuran and Wildlife Poisoning is a collection of meticulously researched papers from all around the world that provide shocking facts about the effects of a deadly insecticide on wildlife. The book discusses the hundreds of thousands of animals, from elephants to fish, that are poisoned each year, the efforts to rehabilitate those which have been rescued, and the often heroic efforts to ban or reduce the use of the deadly chemical. This book is a must for all those concerned with the problem.» —Jane Goodall, PhD, DBE, Founder – the Jane Goodall Institute & UN Messenger of Peace, October 2011

The book offers a comprehensive and user-oriented description of the theoretical and technical system fundamentals of computed tomography (CT) for a wide readership, from conventional single-slice acquisitions to volume acquisition with multi-slice and cone-beam spiral CT. It covers in detail all characteristic parameters relevant for image quality and all performance features significant for clinical application. Readers will thus be informed how to use a CT system to an optimum depending on the different diagnostic requirements. This includes a detailed discussion about the dose required and about dose measurements as well as how to reduce dose in CT. All considerations pay special attention to spiral CT and to new developments towards advanced multi-slice and cone-beam CT. For the third edition most of the contents have been updated and latest topics like dual source CT, dual energy CT, flat detector CT and interventional CT have been added. The enclosed CD-ROM again offers copies of all figures in the book and attractive case studies, including many examples from the most recent 64-slice acquisitions, and interactive exercises for image viewing and manipulation. This book is intended for all those who work daily, regularly or even only occasionally with CT: physicians, radiographers, engineers, technicians and physicists. A glossary describes all the important technical terms in alphabetical order. The enclosed DVD again offers attractive case studies, including many examples from the most recent 64-slice acquisitions, and interactive exercises for image viewing and manipulation. This book is intended for all those who work daily, regularly or even only occasionally with CT: physicians, radiographers, engineers, technicians and physicists. A glossary describes all the important technical terms in alphabetical order.

This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for an individual to research, analyze and synthesize all immense sourcing references. Topics showcase challenges and solutions of issues encountered, offering tremendous experience accumulated over many years of research that will be particularly useful to basic and bench scientists as well as clinicians as they continue discovering and developing new drugs and therapies.

Oral Wound Healing: Cell Biology and Clinical Management brings experts from around the world together to provide an authoritative reference on the processes, principles and clinical management of wound healing in the oral mucosa. Promoting a thorough understanding of current research on the topic, this new resource draws together thinking on the basic biological processes of wound healing in the oral environment, as well as providing more detailed information and discussion on processes such as inflammation, reepithelialization and angiogenesis. Beyond this, the book goes on to examine topics pertinent to the effective clinical management of oral wound healing, bringing together chapters on large dento-facial defects, dental implants, periodontal regeneration, and pulp healing.An essential synthesis of current research and clinical applications, Oral Wound Healing will be an indispensable resource for dental specialists, oral and maxillofacial surgeons as well as researchers in oral medicine and biology.

Sitting an accreditation examination is a daunting prospect for many trainee echocardiographers. And with an increasing drive for the accreditation of echocardiography laboratories and individual echocardiographers, there is a need for an all-encompassing revision aid for those seeking accreditation. The editors of this unique book have produced the only echocardiography revision aid based on the syllabus and format of the British Society of Echocardiography (BSE) national echocardiography accreditation examination and similar examinations administered across Europe. Written by BSE accredited members, fully endorsed by the BSE, and with a foreword by BSE past-president, DR. Simon Ray, this indispensable guide provides a valuable insight into how echocardiography accreditation exams are structured. Crucially, to support students with the more challenging video section of the exam, a companion website provides video cases, and with clear and concisely-structured explanations to all questions, this is an essential tool for anyone preparing to sit an echocardiography examination.