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The revised and updated third edition of the essential guide to the diagnosis and treatment of the diabetic foot The revised third edition of the Atlas of the Diabetic Foot is an updated guide to the information needed for the prevention and treatment of diabetic foot problems with the aim of reducing amputations. In addition to offering the theoretical knowledge, the book is filled with more than 500 color photos from real-life cases. The cases explore a wide-variety of foot issues and the text includes information about differential diagnosis and treatment. The authors—noted experts in the field—describe the epidemiology, pathophysiology and classification of diabetic foot ulcers. In addition, the book highlights the diagnosis of the main risk factors for the diabetic foot, namely diabetic neuropathy, peripheral arterial disease and the anatomic deformities of the lower extremities. The updated third edition, include 5 videos that clearly demonstrate the methods of examination for diabetic neuropathy and peripheral arterial disease. The text incldues methods of callus removal and debridement as well as offloading. In addition, it contains information on how a total contact cast is constructed. This essential resource: Contains a full colour presentation of diabetic foot cases Explains the prevention and treatment of diabetic foot problems in a revised and updated edition Includes a larger format that allows for a better quality images Offers a companion website with high-resolution digital files of photographs of the case studies presented Presents a multidisciplinary approach appropriate for a wide audience foot and diabetic professionals Written for diabetes specialists, endocrinologists and diabetic nurse specialists, podiatrists and podiatry nurse specialists, Atlas of the Diabetic Foot offers the information needed to help with the prevention, diagnosis and management of the diabetic foot.

The definitive guide to the science, diagnosis and treatment of all known nail diseases The fifth edition of Baran & Dawber’s Diseases of the Nails and their Management continues to offer an encyclopedic account of the human nail that is unparalleled in its detail and scope. With contributions from some of the world’s leading dermatologists, the book’s exhaustive coverage encompasses the cosmetic and therapeutic management of every form of nail disease. High-quality images and diagrams illustrate and enhance this essential reference guide, while easy-to-navigate sub-chapters help you to find the information you need quickly and accurately. This book: Is edited by Professor Robert Baran – the world’s leading expert on the human nail – together with a team of world-renowned experts from across Europe and North America Provides clinical information on all nail diseases Aids differential diagnosis by color, shape, and location Contains over 1,500 images Includes access to a companion website featuring downloadable images and videos of nail procedures Whether they are new to the field or have been practicing for years, dermatologists, podiatrists, and all of those managing patients with nail diseases should have a copy of Baran & Dawber’s Diseases of the Nails and their Management at their disposal.

Provides coverage of the pathogenesis, clinical, morphologic, molecular and investigational aspects of a full range of blood disorders seen in daily practice The revised fifth edition of this renowned atlas presents readers with a comprehensive, visual guide to clinical hematology, featuring 2700 full-color photographs and figures depicting the spectrum of hematological diseases. Ranging from photographs of the clinical manifestations and key microscopic findings to diagrams of the molecular aspects of these diseases, the book provides up-to-date information of the blood diseases that clinicians encounter every day. Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease offers the reader an understanding of normal cell machinery, and of the molecular basis for such processes as DNA and cell replication, RNA species, trafficking and splicing, protein synthesis, transcription factors, growth factor signal transduction, epigenetics, cell differentiation, autophagy, and apoptosis. The text goes on to explore how these processes are disturbed in the various diseases of the bone marrow, blood, and lymphoid systems. Helps solve difficult diagnostic challenges and covers complex principles using highly illustrative, full-color images Explores all aspects of benign and malignant hematology, including blood transfusion and coagulation with extensive coverage of the pathogenesis of common clinical entities Provides a quick and easy reference of key diagnostic issues in a comprehensive yet concise format Includes and illustrates the WHO Classification of Hematologic Malignancies Illustrates the new knowledge of the molecular basis of inherited and acquired blood diseases Color Atlas of Clinical Hematology: Molecular and Cellular Basis of Disease is the must-have resource for both trainee and practising hematologists, and for every department of hematology.

The most comprehensive evidence-based guide to both obstetrics and gynecology Aimed at practicing obstetricians, gynecologists, and trainees in the specialty, Evidence-based Obstetrics and Gynecology concentrates on the clinical practice areas of diagnosis, investigation and management. The first section of the book discusses evidence-based medicine methodology in the context of the two specialties. The second and third sections cover all the major conditions in obstetrics and gynecology, with each chapter reviewing the best available evidence for management of the particular condition. The chapters are structured in line with EBM methodology, meaning the cases generate the relevant clinical questions. Evidence-based Obstetrics and Gynecology provides in-depth chapter coverage of abnormal vaginal bleeding; ectopic pregnancy; pelvic pain; lower genital tract infections; contraception and sterilization; breast diseases; urogynecology; endocrinology and infertility; puberty and precocious puberty; cervical dysplasia and HPV; cervical, vaginal, vulvar, uterine, and ovarian cancer; preconception care; prenatal care and diagnosis; drugs and medications in pregnancy; maternal complications; chronic hypertension; diabetes mellitus; thyroid disease; neurologic disease; psychiatric disease; postterm pregnancy; fetal complications; preeclampsia; and more. First book to address evidence-based practice for obstetrics and gynecology combined EBM is a highly relevant approach for this high risk specialty Edited by leading US specialist involved in the evidence-based medicine movement Evidence-Based Obstetrics and Gynecology is an important text for obstetricians and gynecologists in practice and in training, as well as for specialist nurses.

The most comprehensive textbook in the field edited by the founding father of endourology returns for a new edition. In full colour throughout and packed with surgical teaching videos, this is an essential purchase for all urologists wishing to master their skills.

A new volume in the Handbook of Sports Medicine and Science series from the International Olympic Committee, this volume Canoeing provides an accessible and comprehensive summary of the topic. Provides a concise, authoritative overview of the science, medicine and psycho-social aspects of canoeing Offers guidance on medical aspects unique to the training and coaching of canoe athletes The only book on this subject endorsed by the Medical Commission of the International Olympic Committee (IOC) and the International Canoe Federation (ICF) Written and edited by global thought leaders in sports medicine

Physical Assessment for Health Care Professionals offers a practical and comprehensive guide to best clinical practice when taking patient history and physical examination. This accessible text is structured in accordance with the competencies for advanced practice in assessment, diagnosis and treatment as published by the RCN. Following a systematic, systems-based approach to patient assessment, it includes a summary of the key clinical skills needed to develop and improve clinical examination in order to confidently assess, diagnose, plan and provide outstanding care. In this revised edition, colour photographs and case studies have been included to assist health care practitioners in their assessment of the patient. This important guide: Includes a highly visual colour presentation with photographs and illustrations. Features a wide range of key learning points to help guide practice. Offers illustrative examples, applications to practice and case studies. Is available in a range of digital formats – perfect for ‘on the go’ study and reference. Written for health care students, newly qualified and advanced nurse practitioners, and those in the allied health professions, Physical Assessment for Health Care Professionals is the essential guide for developing the skills needed to accurately access patient history and physical examination.

­The authoritative guide for Data Monitoring Committees—fully revised and updated The number of clinical trials sponsored by government agencies and pharmaceutical companies has grown in recent years, prompting an increased need for interim monitoring of data on safety and efficacy. Data Monitoring Committees (DMCs) are an essential component of many clinical trials, safeguarding trial participants and protecting the credibility and validity of the study. Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition offers practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees, providing a practical overview of the establishment, purpose, and responsibilities of these committees. Examination of topics such as the composition and independence of DMCs, statistical, philosophical and ethical considerations, and determining when a DMC is needed, presents readers with a comprehensive foundational knowledge of clinical trial oversight. Providing recent examples to illustrate DMC principles, this fully-updated guide reflects current developments and practices in clinical trial oversight and offers expanded coverage of emerging issues and challenges in the field. This new second edition covers the most current information on DMC policies, issues in monitoring trials using new designs, and recent trial publications relevant to DMC decision-making. • Presents practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees • Illustrates the types of challenging issues Data Monitoring Committees face in practical situations • Provides updated and expanded coverage of topics including regulatory and funding agency guidelines and trial designs and their associated demands and limitations • Includes a new chapter addressing legal issues that affect DMC members and discusses general litigation concerns relevant to clinical research • Expands treatment of current journal publications addressing DMC issues Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition is a must-have text for anyone engaged in DMC activities as well as trial sponsors, clinical trial researchers, regulatory and bioethics professionals, and those associated with clinical trials in academic, government and industry settings.

The essential guide to controlling and managing today’s communicable diseases The fourth edition of Communicable Disease Control and Health Protection Handbook offers public health workers of all kinds an authoritative and up-to-date guide to current protocols surrounding the identification and control of infectious diseases. With its concise, accessible design, the book is a practical tool that can be relied upon to explain topics ranging from the basic principles of communicable disease control to recent changes and innovations in health protection practice. Major syndromes and individual infections are insightfully addressed, while the authors also outline the WHO’s international health regulations and the organizational arrangements in place in all EU nations. New to the fourth edition are chapters on Ebola, the Zika virus, and other emerging pandemics. In addition, new writing on healthcare-associated infection, migrant and refugee health, and the importance of preparedness make this an essential and relevant text for all those in the field. This vital resource: Reflects recent developments in the science and administration of health protection practice Covers topics such as major syndromes, control of individual infections, main services and activities, arrangements for all European countries, and much more Includes new chapters on the Zika virus, Schistosomiasis, Coronavirus including MERS + SARS, and Ebola Follows a format designed for ease of use and everyday consultation Created to provide public and environmental health practitioners, physicians, epidemiologists, infection control nurses, microbiologists and trainees with a straightforward – yet informative – resource, Communicable Disease Control and Health Protection Handbook is a practical companion for all those working the field today.

A timely and topical survey of modern simulation tools and their applications in real-life drug discovery, allowing for better and quicker results in structure-based drug design. The first part of this practical guide for industry professionals describes common tools used in the biomolecular simulation of drugs and their targets. A critical analysis of the accuracy of the predictions, the integration of modeling with other experimental data combined with numerous case studies from different therapeutic fields enable users to quickly adopt these new methods for their current projects. The second part then shows how these tools can be applied to drug discovery and development projects. Modeling experts from the pharmaceutical industry and from leading academic institutions present real-life examples for important target classes such as GPCRs, kinases and amyloids as well as for common challenges in structure-based drug discovery. With its inclusion of novel methods and strategies for the modeling of drug-target interactions in the framework of real-life drug discovery and development, this application-oriented reference is tailor-made for medicinal chemists and those working in the pharmaceutical industry.

The book «Drug Selectivity – An Evolving Concept in Medicinal Chemistry» provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.

На страницах журнала вы найдете народные и традиционные методы лечения и профилактики различных заболеваний, полезную информацию о лекарственных растениях с цветными иллюстрациями, познакомитесь с духовной страничкой. В каждом номере – советы высококвалифицированных специалистов – врачей, психологов, гомеопатов, травников и целителей. У читателей есть возможность бесплатно подать объявления в рубрики «Зов о помощи» и «Для лечения нужны».