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A thorough appreciation of the cellular, molecular and tissue changes which precede the birth of an animal is a fundamental requirement for understanding normal structural development and also abnormal processes which result in congenital defects. This textbook provides information relevant to many subjects taught in preclinical, paraclinical and clinical years. Early chapters describe and explain sequential events relating to the division, growth and differentiation of cells and to the formation of foetal membranes, implantation and placentation. Succeeding chapters trace the origin, growth, development and maturation of the major body systems. Age determination of the embryo and foetus is reviewed in a single chapter. Genetic, chromosomal and environmental factors which adversely affect pre-natal development are reviewed in the final chapter. A reading list at the end of each chapter offers additional sources of information on the topics discussed. Tables, flow diagrams and numerous hand-drawn illustrations provide information in a form which complements the concepts presented in the text. Key features: Written by a team which includes members with expertise in developmental anatomy, molecular biology and clinical aspects of veterinary medicine. The authors have extensive experience in the teaching of veterinary embryology and cognate subjects. Illustrations, hand-drawn by a veterinary graduate, are used extensively to explain organogenesis and system development. An explanatory glossary provides concise information on specialised terms used in the text. The index is designed for easy retrieval of information.

Highly Commended at the British Medical Association Book Awards 2016 Postgraduate Haematology provides up-to-date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style. Up-to-date knowledge of the pathogenesis, clinical and laboratory features and management of all blood disorders New sections reflect advances in the specialty, including knowledge gained from new generation sequencing, latest anticoagulant drugs, diagnostic laboratory tools, and treatment strategies Superb four-color illustrations and photomicrographs of blood cells and tissues throughout Includes algorithms to aid with decision-making for treatment Companion website includes figures and tables for download

Gastrointestinal Emergencies 3E provides practical, up-to-date guidance for gastroenterologists, endoscopists, surgeons, emergency and acute physicians, medical students and trainees managing patients presenting with GI complications and/or emergencies. Combining a symptom section, a specific conditions section and a section that examines complications (and solutions) of GI procedures, focus throughout is on clear, specific how-to guidance, for use before a procedure or immediately after emergency stabilization. An evidence-based approach to presentation, diagnosis and investigation is utilized throughout. New to this third edition are several brand new chapters covering various complications of procedures and specific conditions not previously featured, as well as a thorough look at the many diagnostic and therapeutic advances in recent years. In addition, every chapter from the current edition has undergone wholesale revision to ensure it is updated with the very latest in management guidelines and clinical practice. Once again, full range of emergencies encountered in daily clinical practice will be examined, such as acute pancreatitis, esophageal perforation, capsule endoscopy complications, acute appendicitis, and the difficulties after gastrointestinal procedures. International guidelines from the world’s key gastroenterology societies will be included in relevant chapters. Gastrointestinal Emergencies 3E is the definitive reference guide for the management of gastrointestinal emergencies and endoscopic complications, and the perfect accompaniment for the modern-day gastroenterologist, surgeon, emergency and acute physicians. Every Emergency Department, GI/endoscopy unit, medical/surgical admission unit should keep a copy close at hand for quick reference.

The recipient of much praise and acclaim, Veterinary Parasitology is widely considered to be the definitive veterinary parasitology reference for practitioners and students alike. This Fourth Edition has been developed and enhanced into a two-part reference to reflect recent advances in the field, modern teaching practice, and updated parasite taxonomic classification systems. Part One contains expanded individual parasite descriptions using current taxonomic status within three new chapters on Helminthology, Protozoology and Entomology. Further updated chapters are provided on: The laboratory diagnosis of parasitism, Antiparasitics, The epidemiology of parasitic diseases, and Host resistance to parasitic diseases. Host species chapters have been retained and expanded and are found in Part Two of the edition. KEY FEATURES Tailored for those directly involved in the diagnosis, treatment and control of parasitic diseases of domestic animals Compatible with the diversity of current parasitology teaching modules – both for teaching parasite systematics and diseases on a host-organ basis Offers the most detailed parasite descriptions available today for teachers, research groups, veterinarians in practice and in government service, and others involved in aspects of parasitic disease Thoroughly revised and restructured to reflect the most up-to-date advancements in the field, Veterinary Parasitology, Fourth Edition, enhances its stellar reputation as the gold standard reference text for the global veterinary profession.

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the fundamentals, computational approaches and their applications, this volume provides expert accounts of the latest experimental methods for investigating drug metabolism in four dedicated chapters. The authors discuss the most important caveats and common errors to consider when working with experimental data. Collating the knowledge gained over the past decade, this practice-oriented guide presents methods not only used in drug development, but also in the development and toxicological assessment of cosmetics, functional foods, agrochemicals, and additives for consumer goods, making it an invaluable reference in a variety of disciplines.

Epilepsy requires careful management and monitoring through a woman’s life Epilepsy is a complex disease. The hormonal changes women experience, both day-to-day menstrual fluctuations and the longer waxes and wanings of a reproductive lifetime, make the management of epilepsy even more complicated. At some point, the well-being of a second person, a fetus, might also have to be taken into account. Epilepsy in Women provides a detailed guide to this challenge. The wide-ranging approach encompasses all aspects of a woman’s life including: Social and psychological impacts The impact in reproductive life Contraception Pregnancy Fetal health and long term developmental outcomes Lactation Menopause Each practical chapter begins and ends with a case study that demonstrates the more general challenge. The authors develop themes to provide clinical guidance based on evidence and experience. Written and edited by an international cast of experts, Epilepsy in Women provides crucial tips and recommendations for neurologists and gynecologists who need to be aware of the subtle effects of epilepsy on woman’s life.

The psychiatric profession must ensure that its next generation of leaders has the appropriate skills to provide mental health services in the face of globalization and urbanization, new technologies, and competing demands for shrinking resources. Developing leadership skills and leaders is critical in order to optimise the use of resources, their application, service planning and delivery of services for patients and their families. This is the first book on leadership (rather than management skills) to focus on psychiatry and mental health care. Contributions from international experts with clinical and non-clinical backgrounds pull together the theories and practical skills required to be a successful leader. The aim is to guide mental health professionals in general and psychiatrists in particular on how to gain the relevant skills and on how to utilise these skills and training to take on leadership roles in clinical and organisational settings. The book covers the role of the leader and the skills required for leadership, including chapters on communication, decision-making, team development, mentoring, gender issues in leadership, burnout and more. It includes a section on assessment tools and learning material. Essential reading for all those who aspire to lead in psychiatry!

Rare gynecological cancers kill all too commonly Gynecological cancer is a frightening prospect for women. It is terrifying also for physicians who need, but often can’t find, guidance on how to investigate and appropriately treat the tumors. Rare cancers provide greater challenges as information can be harder to find and more difficult to verify. Rare Gynecologic Cancers: Diagnosis and Management brings together all you need to know on these life-threatening diseases. Straightforward summaries of pathophysiologic processes lead to the investigations that will improve your diagnostic accuracy. This provides the basis for you to identify effective treatment strategies for your patients. Written by a world-leading team of Editors and Authors and covering cancers of the • Ovaries • Uterus • Vulva • Vagina • Cervix Rare Gynecologic Cancers: Diagnosis and Management will guide you to the best life-saving treatment for your patients.

Now fully revised and updated, Bioethics: An Anthology, 3rd edition, contains a wealth of new material reflecting the latest developments. This definitive text brings together writings on an unparalleled range of key ethical issues, compellingly presented by internationally renowned scholars. The latest edition of this definitive one-volume collection, now updated to reflect the latest developments in the field Includes several new additions, including important historical readings and new contemporary material published since the release of the last edition in 2006 Thematically organized around an unparalleled range of issues, including discussion of the moral status of embryos and fetuses, new genetics, neuroethics, life and death, resource allocation, organ donations, public health, AIDS, human and animal experimentation, genetic screening, and issues facing nurses Subjects are clearly and captivatingly discussed by globally distinguished bioethicists A detailed index allows the reader to find terms and topics not listed in the titles of the essays themselves

The fifth edition of this practical textbook on transfusion medicine has been thoroughly revised with the latest in scientific and technological developments and edited by a leading team of international expert haematologists, including new co-editor Mark H. Yazer MD. A succinct and user-friendly resource of transfusion medicine for clinicians, scientists and trainees with key points, charts and algorithms Discusses practice in blood centres and hospitals including regulatory aspects, transfusion safety, production and storage, donor care, and blood transfusion in a global context Coverage of cellular and tissue therapies and organ transplantation including stem cell collection and haematopoietic stem cell processing and storage Review of the development of the evidence-base for transfusion medicine Content on the clinical practice for transfusion and alternatives to transfusion

This new edition of the popular and market-leading Diabetes in Old Age features up-to-date and comprehensive information about the key aspects of managing older people with diabetes, predominantly type 2 diabetes. With a strong evidence-based focus throughout, the entire range of issues surrounding diabetes and its many complications are covered, each with a clear focus on how they relate directly to the older patient. Varying approaches to optimizing diabetes care in the community, primary care and secondary care health care arenas are presented, and the importance of comprehensive functional assessment is emphasized. Coverage of areas unique to an ageing population of older people with diabetes such as falls management, frailty and sarcopenia, and cognitive dysfunction form a key cornerstone of the book. In every chapter, best practice points and key learning outcomes are provided, as well as published evidence bases for each major conclusion. Diabetes in Old Age, 4th edition is essential reading for diabetologists and endocrinologists, diabetes specialist nurses, primary care physicians, general physicians and geriatricians, podiatrists and dieticians with an interest in diabetes, as well as all health professionals engaged in the delivery of diabetes care to older people.

This advanced textbook is tailored for an introductory course in Systems Biology and is well-suited for biologists as well as engineers and computer scientists. It comes with student-friendly reading lists and a companion website featuring a short exam prep version of the book and educational modeling programs. The text is written in an easily accessible style and includes numerous worked examples and study questions in each chapter. For this edition, a section on medical systems biology has been included.