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Written in four parts, this book provides a dedicated and in-depth reference for blending within the pharmaceutical manufacturing industry. It links the science of blending with regulatory requirements associated with pharmaceutical manufacture. The contributors are a combination of leading academic and industrial experts, who provide an informed and industrially relevant perspective of the topic. This is an essential book for the pharmaceutical manufacturing industry, and related academic researchers in pharmaceutical science and chemical and mechanical engineering.

In many Western diets, the role of plants has been reduced in favour of more animal-based products and this is now being cited more widely as being the cause of increases in the incidence of diseases such as cancer and cardiovascular disease. This important book covers the biochemistry and nutritional importance of a wide range of phytonutrients, including all the major macronutrients as well as the micronutrients and 'non-essential' nutrients. Phytonutrients is divided into three parts. The first deals with the role of plants in the human diet. Part II, representing the major part of the book covers in turn each of the major phytonutrient groups. Chapters include: non-lipid micronutrients, lipids and steroids, carotenoids, phenolics, vitamins C, E, folate/vitamin B12, phytoestrogens, other phytonutrients and minerals, and anti-nutritional factors. The final part of the book covers the methods used to manipulate levels of phytonutrients in the diet, such as fortification, supplementation and the use of genetically modified plants. Phytonutrients is an essential purchase for nutritionists, food scientists and plant biochemists, particularly those dealing with nutrients from plants, and their use in the human diet.

The pioneering guide on the design, processing, and testing of antimicrobial plastic materials and coatings The manifestation of harmful microbes in plastic materials used in medical devices and drugs, water purification systems, hospital equipment, textiles, and food packaging pose alarming health threats to consumers by exposing them to many serious infectious diseases. As a result, high demand for intensifying efforts in the R&D of antimicrobial polymers has placed heavy reliance on both academia and industry to find viable solutions for producing safer plastic materials. To assist researchers and students in this endeavor, Antimicrobial Polymers explores coupling contaminant-deterring biocides and plastics—focusing particular attention on natural biocides and the nanofabrication of biocides. Each chapter is devoted to addressing a key technology employed to impart antimicrobial behavior to polymers, including chemical modification of the polymers themselves. A host of relevant topics, such as regulatory matters, human safety, and environmental risks are covered to help lend depth to the book's vital subject matter. In addition, Antimicrobial Polymers: Discusses the design, processing, and testing of antimicrobial plastic materials Covers interdisciplinary areas of chemistry and microbiology Includes applications in food packaging, medical devices, nanotechnology, and coatings Details regulations from the U.S. (FDA and EPA) and EU as well as human safety and environmental concerns Achieving cleaner and more effective methods for improving the infection-fighting properties of versatile and necessary plastic materials is a goal that stretches across many scientific fields. Antimicrobial Polymers combines all of this information into one volume, exposing readers to preventive strategies that harbor vast potential for making exposure to polymeric products and surfaces a far less risky undertaking in the future.

A NEW EDITION OF THE CLASSIC TEXT ON OPTIMAL CONTROL THEORY As a superb introductory text and an indispensable reference, this new edition of Optimal Control will serve the needs of both the professional engineer and the advanced student in mechanical, electrical, and aerospace engineering. Its coverage encompasses all the fundamental topics as well as the major changes that have occurred in recent years. An abundance of computer simulations using MATLAB and relevant Toolboxes is included to give the reader the actual experience of applying the theory to real-world situations. Major topics covered include: Static Optimization Optimal Control of Discrete-Time Systems Optimal Control of Continuous-Time Systems The Tracking Problem and Other LQR Extensions Final-Time-Free and Constrained Input Control Dynamic Programming Optimal Control for Polynomial Systems Output Feedback and Structured Control Robustness and Multivariable Frequency-Domain Techniques Differential Games Reinforcement Learning and Optimal Adaptive Control

Materials Processing Fundamentals provides researchers and industry professionals with complete guidance on the synthesis, analysis, design, monitoring, and control of metals, materials, and metallurgical processes and phenomena. Along with the fundamentals, it covers modeling of diverse phenomena in processes involving iron, steel, non-ferrous metals, and composites. It also goes on to examine second phase particles in metals, novel sensors for hostile-environment materials processes, online sampling and analysis techniques, and models for real-time process control and quality monitoring systems.

With both nickel and cobalt featuring heavily in modern industry, there is an ongoing and intense interest in ore supplies and processing, applications development, and recycling. This book presents a collection of authoritative papers covering the latest advances in all aspects of nickel and cobalt processing, including fundamentals, technology, operating practices, and related areas of Platinum-Group Metals (PGM) processing. Special emphasis is given to the treatment of sulphide and laterite ores, concentrates, and secondary materials for the production of nickel and cobalt.

Wireless telecommunication systems generate a huge amount of interest. In the last two decades, these systems have experienced at least three major technological leaps, and it has become impossible to imagine how society was organized without them. In this book, we propose a macroscopic approach on wireless systems, and aim at answering key questions about power, data rates, multiple access, cellular engineering and access networks architectures. We present a series of solved problems, whose objective is to establish the main elements of a global link budget in several radiocommunications systems. Contents 1. Radio Propagation. 2. F/TDMA and GSM. 3. CDMA and UMTS. 4. OFDM and LTE. 5. MIMO and Beamforming. 6. UWB. 7. Synchronization. 8. Digital Communications Fundamentals. 9. Erlang B Tables. About the Authors Michel Terré received his engineering degree from Télécom SudParis, his phD in electronics and telecommunications from Conservatoire National des Arts et Métiers (CNAM), and his habilitation to conduct researches from Paris XIII University. He is a full professor at Conservatoire National des Arts et Métiers. He his responsabile of CNAM’s Master of Science in radiocommunicationssystems. Mylène Pischella received her engineering degree and her phD in electronics and telecommunications from Télécom ParisTech. She is an associate professor at Conservatoire National des Arts et Métiers (CNAM). Emmanuelle Vivier received her engineering degree from Institut Supérieur d’Electronique de Paris (ISEP) and her PhD in radiocommunications from Conservatoire National des Arts et Métiers (CNAM). She is an associate professor at ISEP, where she is responsible of networks and telecommunications teaching majors.

This much-needed book describes the digital home networking environment, its techniques, and the challenges around its service architecture. It provides a broad introduction to state-of-the-art digital home standards and protocols, as well as in-depth coverage of service architectures for entertainment and domotic services involving digital home resources. Topics include networking, remote access, security, interoperability, scalability, and quality of service. Notably, the book describes the generic architecture that was proposed and developed in the context of the EUREKA/Celtic research project Feel@Home.

This book aims at describing the wide variety of new technologies and concepts of non-standard antenna systems – reconfigurable, integrated, terahertz, deformable, ultra-wideband, using metamaterials, or MEMS, etc, and how they open the way to a wide range of applications, from personal security and communications to multifunction radars and towed sonars, or satellite navigation systems, with space-time diversity on transmit and receive. A reference book for designers in this lively scientific community linking antenna experts and signal processing engineers.

With a focus on actual industrial processes, e.g. the production of light alkenes, synthesis gas, fine chemicals, polyethene, it encourages the reader to think “out of the box” and invent and develop novel unit operations and processes. Reflecting today’s emphasis on sustainability, this edition contains new coverage of biomass as an alternative to fossil fuels, and process intensification. The second edition includes: New chapters on Process Intensification and Processes for the Conversion of Biomass Updated and expanded chapters throughout with 35% new material overall Text boxes containing case studies and examples from various different industries, e.g. synthesis loop designs, Sasol I Plant, Kaminsky catalysts, production of Ibuprofen, click chemistry, ammonia synthesis, fluid catalytic cracking Questions throughout to stimulate debate and keep students awake! Richly illustrated chapters with improved figures and flow diagrams Chemical Process Technology, Second Edition is a comprehensive introduction, linking the fundamental theory and concepts to the applied nature of the subject. It will be invaluable to students of chemical engineering, biotechnology and industrial chemistry, as well as practising chemical engineers. From reviews of the first edition: “The authors have blended process technology, chemistry and thermodynamics in an elegant manner… Overall this is a welcome addition to books on chemical technology.” – The Chemist “Impressively wide-ranging and comprehensive… an excellent textbook for students, with a combination of fundamental knowledge and technology.” – Chemistry in Britain (now Chemistry World)

This text provides a basic treatment of modern electric machine analysis that gives readers the necessary background for comprehending the traditional applications and operating characteristics of electric machines—as well as their emerging applications in modern power systems and electric drives, such as those used in hybrid and electric vehicles. Through the appropriate use of reference frame theory, Electromagnetic Motion Devices, Second Edition introduces readers to field-oriented control of induction machines, constant-torque, and constant-power control of dc, permanent-magnet ac machines, and brushless dc machines. It also discusses steady-state and transient performance in addition to their applications. Electromagnetic Motion Devices, Second Edition presents: The derivations of all machine models, starting with a common first-principle approach (based upon Ohm's, Faraday's, Ampere's, and Newton's/Euler's laws) A generalized two-phase approach to reference frame theory that can be applied to the ac machines featured in the book The influences of the current and voltage constraints in the torque-versus-speed profile of electric machines operated with an electric drive Complete with slides, videos, animations, problems & solutions Thoroughly classroom tested and complete with a supplementary solutions manual and video library, Electromagnetic Motion Devices, Second Edition is an invaluable book for anyone interested in modern machine theory and applications. If you would like access to the solutions manual and video library, please send an email to: [email protected].

Control theory is the main subject of this title, in particular analysis and control design for hybrid dynamic systems. The notion of hybrid systems offers a strong theoretical and unified framework to cope with the modeling, analysis and control design of systems where both continuous and discrete dynamics interact. The theory of hybrid systems has been the subject of intensive research over the last decade and a large number of diverse and challenging problems have been investigated. Nevertheless, many important mathematical problems remain open. This book is dedicated mainly to hybrid systems with constraints; taking constraints into account in a dynamic system description has always been a critical issue in control. New tools are provided here for stability analysis and control design for hybrid systems with operating constraints and performance specifications. Contents 1. Positive Systems: Discretization with Positivity and Constraints, Patrizio Colaneri, Marcello Farina, Stephen Kirkland, Riccardo Scattolini and Robert Shorten. 2. Advanced Lyapunov Functions for Lur’e Systems, Carlos A. Gonzaga, Marc Jungers and Jamal Daafouz. 3. Stability of Switched DAEs, Stephan Trenn. 4. Stabilization of Persistently Excited Linear Systems, Yacine Chitour, Guilherme Mazanti and Mario Sigalotti. 5. Hybrid Coordination of Flow Networks, Claudio De Persis, Paolo Frasca. 6. Control of Hybrid Systems: An Overview of Recent Advances, Ricardo G. Sanfelice. 7. Exponential Stability for Hybrid Systems with Saturations, Mirko Fiacchini, Sophie Tarbouriech, Christophe Prieur. 8. Reference Mirroring for Control with Impacts, Fulvio Forni, Andrew R. Teel, Luca Zaccarian. About the Authors Jamal Daafouz is an expert in the area of switched and polytopic systems and has published several major results in leading journals (IEEE TAC, Automatica, Systems and Control Letters, etc.). He serves as an Associate Editor for the key journal IEEE TAC and is a member of the Editorial Board of the IEEE CSS society. Sophie Tarbouriech is an expert in the area of nonlinear systems with constraints and has published several major results in leading journals (IEEE TAC, Automatica, Systems and Control Letters, etc.) and books. She is a member of the Editorial Board of the IEEE CSS society and has also served as an Associate Editor for the key journal IEEE TAC. Mario Sigalotti is an expert in applied mathematics and switched systems and has published several results in leading journals (IEEE TAC, Automatica, Systems and Control Letters, etc.). He heads the INRIA team GECO and is a member of the IFAC Technical Committee on Distributed Parameter Systems.