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The creation of affordable high speed optical communications using standard semiconductor manufacturing technology is a principal aim of silicon photonics research. This would involve replacing copper connections with optical fibres or waveguides, and electrons with photons. With applications such as telecommunications and information processing, light detection, spectroscopy, holography and robotics, silicon photonics has the potential to revolutionise electronic-only systems. Providing an overview of the physics, technology and device operation of photonic devices using exclusively silicon and related alloys, the book includes: Basic Properties of Silicon Quantum Wells, Wires, Dots and Superlattices Absorption Processes in Semiconductors Light Emitters in Silicon Photodetectors , Photodiodes and Phototransistors Raman Lasers including Raman Scattering Guided Lightwaves Planar Waveguide Devices Fabrication Techniques and Material Systems Silicon Photonics: Fundamentals and Devices outlines the basic principles of operation of devices, the structures of the devices, and offers an insight into state-of-the-art and future developments.

Patients with intellectual disability (ID) can benefit from the full range of mental health services. To ensure that psychiatric assessment, diagnosis and treatment interventions are relevant and effective; individuals with ID should be evaluated and treated within the context of their developmental framework. Behavior should be viewed as a form of communication. Individuals with ID often present with behavioral symptoms complicated by limited expressive language skills and undiagnosed medical conditions. Many training programs do not include focused study of individuals with ID, despite the fact that patients with ID will be seen by virtually every mental health practitioner. In this book, the authors present a framework for competent assessment and treatment of psychiatric disorders in individuals with ID. Psychiatry of Intellectual Disability is a resource guide for psychiatrists, nurse practitioners, and other prescribers treating patients with ID. It is a supplemental text for psychiatry residents, medical students, psychology graduate students, psychotherapists, counselors, social workers, behavior support specialists and nurses. To assist the practicing clinician the book includes: Clinical vignettes Clinical pearls Charts for quick reference Issues concerning medications and poly-pharmacy Altered diagnostic criteria specific for use with individuals with ID There are no evidence-based principles dedicated to psychotropic medication use in ID, but consensus guidelines address the high prevalence of poly-pharmacy. Altered diagnostic criteria have been published which accommodate less self-report and incorporate collateral information; this book reviews the literature on psychotropic medications, consensus guidelines, and population-specific diagnostic criteria sets. Psychiatry of Intellectual Disability also includes: Interviewing techniques and assessment tips for all levels of communicative ability as well as for nonverbal individuals Assessment of aggression to determine etiology and formulate a treatment plan Overview of types of psychotherapy and suggested alterations for each to increase efficacy Relevant legal issues for caregivers and treatment providers The detective work involved in mental health assessment of individuals with ID is challenging yet rewarding. The highest quality mental health treatment limits hospital days, improves quality of life and often allows individuals to live in the least restrictive environments. Psychiatry of Intellectual Disability is a must have resource for clinicians treating the ID population.

This third volume in the successful 'Drug Discovery in Infectious Diseases' series is the first to deal with drug discovery in helminthic infections in human and animals. The result is a broad overview of different drug target evaluation methods, including specific examples of successful drug development against helminthes, and with a whole section devoted to vaccine development. With its well-balanced mix of high-profile contributors from academia and industry, this handbook and reference will appeal to a wide audience, including parasitologists, pharmaceutical industry, epidemiologists, and veterinary scientists.

This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.

The output from world aquaculture, a multi-billion dollar global industry, continues to rise at a very rapid rate and it is now acknowledged that it will take over from fisheries to become the main source of animal and plant products from aquatic environments in the future. Since the first edition of this excellent and successful book was published, the aquaculture industry has continued to expand at a massive rate globally and has seen huge advances across its many and diverse facets. This new edition of Aquaculture: Farming Aquatic Animals and Plants covers all major aspects of the culture of fish, shellfish and algae in freshwater and marine environments. Subject areas covered include principles, water quality, environmental impacts of aquaculture, desert aquaculture, reproduction, life cycles and growth, genetics and stock improvement, nutrition and feed production, diseases, vaccination, post-harvest technology, economics and marketing, and future developments of aquaculture. Separate chapters also cover the culture of algae, carps, salmonids, tilapias, channel catfish, marine and brackish fishes, soft-shelled turtles, marine shrimp, mitten crabs and other decapod crustaceans, bivalves, gastropods, and ornamentals. There is greater coverage of aquaculture in China in this new edition, reflecting China's importance in the world scene. For many, Aquaculture: Farming Aquatic Animals and Plants is now the book of choice, as a recommended text for students and as a concise reference for those working or entering into the industry. Providing core scientific and commercially useful information, and written by around 30 internationally-known and respected authors, this expanded and fully updated new edition of Aquaculture is a book that is essential reading for all students and professionals studying and working in aquaculture. Fish farmers, hatchery managers and all those supplying the aquaculture industry, including personnel within equipment and feed manufacturing companies, will find a great deal of commercially useful information within this important and now established book. Reviews of the First Edition «This exciting, new and comprehensive book covers all major aspects of the aquaculture of fish, shellfish and algae in freshwater and marine environments including nutrition and feed production.» —International Aquafeed «Do we really need yet another book about aquaculture? As far as this 502-page work goes, the answer is a resounding 'yes'. This book will definitely find a place in university libraries, in the offices of policy-makers and with economists looking for production and marketing figures. Fish farmers can benefit greatly from the thematic chapters, as well as from those pertaining to the specific plant or animal they are keeping or intending to farm. Also, they may explore new species, using the wealth of information supplied.» —African Journal of Aquatic Science «Anyone studying the subject or working in any way interested in aqua

If a colleague were to ask me, What would you recommend I read if I want to become a real expert on bipolarity?" I would respond Bipolar Psychopharmacotherapy: Caring for the Patient." Journal of Bipolar Disorders And the second edition is even better! Bipolar Psychopharmacotherapy covers both pharmacotherapy and the supportive role of psychotherapy, psychoeducation and social approaches to provide a broad integrative philosophy of care for bipolar patients. Extensive coverage is given to special management issues such as the pharmacological care of women with bipolar disorder, children and the elderly, as well as bipolar depression and suicide prevention. The mood swings that characterize bipolar disorder can now be better stabilized in most patients than in the past, but the illness must be carefully managed throughout a person's life. Pharmacotherapy is central to the acute treatment and long-term management and as there are several classes of drugs which are often prescribed concurrently, treatment issues are complex. This essential reference work features critical reviews of the existing literature, plus information on new treatments that have been reported at peer reviewed scientific meetings, often written by the pioneering experts on a particular treatment. The second-generation antipsychotics are now covered in separate chapters to provide in-depth coverage of these agents. There are also new chapters on the pharmacological treatments of mixed states and rapid cycling and novel therapeutic vistas.

A growing awareness of the relationship between diet and health has led to an increasing demand for food products that support health beyond simply providing basic nutrition. Digestive health is the largest segment of the burgeoning functional food market worldwide. Incorporation of bioactive oligosaccharides into foods can yield health benefits in the gastrointestinal tract and other parts of the body that are linked via the immune system. Because oligosaccharides can be added to a wide variety of foodstuffs, there is much interest within the food industry in incorporating these functional ingredients into healthy food products. Moreover, other areas such as pharmaceuticals, bioenergy and environmental science can exploit the physicochemical and physiological properties of bioactive oligosaccharides too. There is therefore a considerable demand for a concentrated source of information on the development and characterization of new oligosaccharides with novel and/or improved bioactivities. Food Oligosaccharides: Production, Analysis and Bioactivityis a comprehensive reference on the naturally occurring and synthesised oligosaccharides, which will enable food professionals to select and use these components in their products. It is divided into three sections: (i) Production and bioactivity of oligosaccharides, (ii) Analysis and (iii) Prebiotics in Food Formulation. The book addresses classical and advanced techniques to structurally characterize and quantitatively analyse food bioactive oligosaccharides. It also looks at practical issues faced by food industry professionals seeking to incorporate prebiotic oligosaccharides into food products, including the effects of processing on prebiotic bioavailability. This book is essential reading for food researchers and professionals, nutritionists and product developers working in the food industry, and students of Food Science with an interest in functional foods.

The magnitude of investment, the long time-frames involved and the influence of pre-existing infrastructure on urban infrastructure provision make a co-ordinated approach to forward-planning, policy development and implementation essential. There are major challenges in making decisions on urban infrastructure and getting management structures and processes in place. Getting it right generates long-term dividends; getting it wrong involves major costs, often borne by taxpayers. Urban Infrastructure: finance and management is posited on a strong belief that the physical structure of cities and the efficiency of infrastructure services delivered are driven by efficiencies within individual infrastructure sectors, lessons learnt across these sectors and the ability to co-ordinate and integrate sectors to generate economies of scale. This necessitates an interdisciplinary approach, integrating knowledge from finance, governance, planning and management as well as the characteristics of the individual urban infrastructure sectors involved. Here it is not only about getting the initial decisions and policy settings right, but also ensuring effective implementation. A major theme running through the book is the nature of institutions and the governance structures responsible for delivery and management of urban infrastructure and the decision making processes involved. The editors have taken a deliberately pragmatic approach to the finance and management of urban infrastructure; chapters are cross-sectorial and present both theory and practice. This book is for students and practitioners in policy, planning, urban management, infrastructure finance and management.

Fiber-optic communication systems have advanced dramatically over the last four decades, since the era of copper cables, resulting in low-cost and high-bandwidth transmission. Fiber optics is now the backbone of the internet and long-distance telecommunication. Without it we would not enjoy the benefits of high-speed internet, or low-rate international telephone calls. This book introduces the basic concepts of fiber-optic communication in a pedagogical way. The important mathematical results are derived by first principles rather than citing research articles. In addition, physical interpretations and real-world analogies are provided to help students grasp the fundamental concepts. Key Features: Lucid explanation of key topics such as fibers, lasers, and photodetectors. Includes recent developments such as coherent communication and digital signal processing. Comprehensive treatment of fiber nonlinear transmission. Worked examples, exercises, and answers. Accompanying website with PowerPoint slides and numerical experiments in MATLAB. Intended primarily for senior undergraduates and graduates studying fiber-optic communications, the book is also suitable as a professional resource for researchers working in the field of fiber-optic communications.

The Physics of Microdroplets gives the reader the theoretical and numerical tools to understand, explain, calculate, and predict the often nonintuitive observed behavior of droplets in microsystems. Microdrops and interfaces are now a common feature in most fluidic microsystems, from biology, to biotechnology, materials science, 3D-microelectronics, optofluidics, and mechatronics. On the other hand, the behavior of droplets and interfaces in today's microsystems is complicated and involves complex 3D geometrical considerations. From a numerical standpoint, the treatment of interfaces separating different immiscible phases is difficult. After a chapter dedicated to the general theory of wetting, this practical book successively details: The theory of 3D liquid interfaces The formulas for volume and surface of sessile and pancake droplets The behavior of sessile droplets The behavior of droplets between tapered plates and in wedges The behavior of droplets in microchannels The effect of capillarity with the analysis of capillary rise The onset of spontaneous capillary flow in open microfluidic systems The interaction between droplets, like engulfment The theory and application of electrowetting The state of the art for the approach of 3D-microelectronics using capillary alignment

Up-to-date coverage of bridge design and analysis— revised to reflect the fifth edition of the AASHTO LRFD specifications Design of Highway Bridges, Third Edition offers detailed coverage of engineering basics for the design of short- and medium-span bridges. Revised to conform with the latest fifth edition of the American Association of State Highway and Transportation Officials (AASHTO) LRFD Bridge Design Specifications, it is an excellent engineering resource for both professionals and students. This updated edition has been reorganized throughout, spreading the material into twenty shorter, more focused chapters that make information even easier to find and navigate. It also features: Expanded coverage of computer modeling, calibration of service limit states, rigid method system analysis, and concrete shear Information on key bridge types, selection principles, and aesthetic issues Dozens of worked problems that allow techniques to be applied to real-world problems and design specifications A new color insert of bridge photographs, including examples of historical and aesthetic significance New coverage of the «green» aspects of recycled steel Selected references for further study From gaining a quick familiarity with the AASHTO LRFD specifications to seeking broader guidance on highway bridge design—Design of Highway Bridges is the one-stop, ready reference that puts information at your fingertips, while also serving as an excellent study guide and reference for the U.S. Professional Engineering Examination.

Schizophrenia is one of the most complex and disabling diseases to affect mankind. Relatively little is known about its nature and its origins, and available treatments are inadequate for most patients. As a result, there are inevitable controversies about what causes it, how to diagnose it, and how best to treat it. However, in the past decade, there has been an explosion of new research, with dramatic discoveries involving genetic etiology and epidemiological risk factors. There has also been a catalog of new drugs coming to market, and controversy about the relative advantages and disadvantages of newer compared with older therapies. In addition, developing technologies in genomics, molecular biology and neuroimaging provide streams of new information. This book represents a definitive, essential, and up-to-date reference text on schizophrenia. It extensively and critically digests and clarifies recent advances and places them within a clinical context. The Editors (one American and one British), highly respected clinical psychiatrists and researchers and acknowledged experts on schizophrenia, have again assembled an outstanding group of contributors from the USA, UK, Europe and Australia, It will be of value to practising psychiatrists and to trainees, as well as to clinical and neuroscience researchers interested in keeping up with this field or coming into it. The book consists of four sections: descriptive aspects, biological aspects, physical treatments, and psychological and social aspects. It reviews the theoretical controversies over symptomatology, classification and aetiology (particularly pertinent as DSM-V is being developed), the relationship of schizophrenia to the other psychoses, the significance of positive and negative symptoms and pre-morbid personality. It describes a variety of approaches to integrating the vast research data about schizophrenia, including neurodevelopmental, genetic, pharmacological, brain imaging and psychological findings. The biological treatment section reviews the comparative efficacy of various drugs, the management of drug-resistant patients and both neurological and metabolic complications. The final section looks at psychological therapies, social outcomes, and the economics of schizophrenia. Highly Commended in the Psychiatry section of the 2012 BMA Book Awards.