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Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protection, key analytical approaches, the role of ethnopharmacology in primary/secondary education and links to biodiversity and ecological research. Part two looks at ethnopharmacological contributions to modern therapeutics across a range of conditions including CNS disorders, cancer, bone and joint health and parasitic diseases. The final part is devoted to regional perspectives covering all continents, providing a state-of-the –art assessment of the status of ethnopharmacological research globally. A comprehensive, critical synthesis of the latest developments in ethnopharmacology. Includes a section devoted to ethnopharmacological contributions to modern therapeutics across a range of conditions. Contributions are from leading international experts in the field. This timely book will prove invaluable for researchers and students across a range of subjects including ethnopharmacology, ethnobotany, medicinal plant research and natural products research. Ethnopharmacology- A Reader is part of the ULLA Series in Pharmaceutical Sciences www.ullapharmsci.org

The second edition of Clinical Arrhythmology provides a fresh, clear, and authoritative overview that will guide readers from a solid understanding of the mechanisms behind cardiac arrhythmias – which is fundamental to their identification – to diagnosis via electrocardiograms and other tools, to specific management options for each of the arrhythmias that cardiologists and other clinicians will encounter in clinical practice. Organized in a clear, intuitive manner; introducing the reader to an understanding of the anatomical and electrophysiological bases of arrhythmias, then to a comprehensive review of how to diagnose the full range of rhythmic abnormalities, and then to a discussion of specific clinical syndromes in which arrhythmias play a part Highly illustrated chapters ensure key concepts are simpler to understand Detailed appendices provide quick reference values for diagnostic and therapeutic techniques, and pharmacotherapeutic agents, and Recommendations

From the bestselling author, Barbara J. Bain, the new edition of this practical reference on the principles of leukaemia diagnosis and classification has been fully updated, and incorporates the recently revised WHO classification. Leukaemias are a very heterogeneous group of diseases, which differ from each other in aetiology, pathogenesis, prognosis and responsiveness to treatment. Accurate diagnosis and classification are vital for the identification of specific biological entities and underpin scientific advances in this field. The detailed characterization of haematological neoplasms is also essential for the optimal management of individual patients. In this user-friendly guide, Professor Bain illustrates and explains how these many laboratory techniques are used for the diagnosis and classification of leukaemia and related disorders. Leukaemia Diagnosis, Fifth Edition will be highly valuable to trainee haematologists and laboratory scientists in haematology and related disciplines, and will also prove a useful reference source and teaching aid for those who already have expertise in this field. In addition, cytogeneticists and molecular geneticists will find that this book enhances their understanding of the relationship of their disciplines to the diagnosis, classification and monitoring of leukaemia and related disorders. Essential reading for every haematologist and haematopathologist, Leukaemia Diagnosis, Fifth Edition features Over 300 high quality full colour digital images of abnormal cells in leukaemia and lymphoma supplemented by histological, cytogenetic and immunophenotyping images Recent information on cytogenetic and molecular genetic abnormalities in leukaemia Updated information on the characteristic immunophenotypic characteristics of different categories of leukaemia

A must have resource for clinicians and investigators interested in pulmonary embolism and deep venous thrombosis Highly illustrated with numerous tables and graphs alongside clear concise text Includes chapters addressing pulmonary embolism (PE) and deep venous thrombosis (DVT) in relation to diseases and disorders such as; chronic heart failure, cancer, diabetes, stroke, chronic obstructive pulmonary disease (COPD) and many more Discusses the role the different tools offered in imaging for PE, including echocardiography, multidetector computed tomography (CT), single photon emission computed tomography (SPECT), ventilation-perfusion (V-Q) imaging, dual energy CT, and magnetic resonance angiography Contains 29 new chapters and includes new content on epidemiology of deep venous thrombosis; use of the new anticoagulants (dabigatran, rivaroxaban, and apixaban) for DVT and PE; indications and results with thrombolytic therapy and with vena cava filters; and information and indications for invasive mechanical thrombectomy and thrombolysis Written by an internationally recognized and respected expert in the field

Thoroughly updated to reflect recent changes in the industry, Bovine Medicine, 3rd Edition, offers practicing large animal veterinarians and veterinary students a comprehensive reference to core aspects of contemporary cattle health and husbandry. New edition of a classic text, featuring thoroughly rewritten text, with coverage shifted to the core aspects of everyday cattle practice Includes new focus on both applied skills and application of knowledge, along with many more full-colour illustrations than in previous editions Represents a toolkit of skills that will support the delivery of contemporary cattle practice Presents a seamless integration of information on husbandry, nutrition, and disease Written by a wide range of experts from around the world

Jubilee edition of the classic text first published in 1963 Anaesthetists require a particularly specialized knowledge of anatomy The anaesthetist must know intimately the respiratory passages, the major veins and the peripheral nerves to deliver safe and effective pain control. As one of the great teachers of anatomy, Professor Harold Ellis is eminently qualified to elegantly provide the anatomical detail required of anaesthetists. Modern approaches to practice, including the use of imaging to guide anaesthetic practice, add further depth to the fine full-colour anatomical illustrations. Designed for anaesthetists, Anatomy for Anaesthetists covers: • The Respiratory Pathway, Lungs, Thoracic Wall and Diaphragm • The Heart and Great Veins of the Neck • The Peripheral Nerves • The Autonomic Nervous System • The Cranial Nerves • The Anatomy of Pain Clinical Notes throughout provide the clinical context for the anatomical detail. Designed for trainees, but of continuing relevance to practicing anaesthetists, and now in its Golden Jubilee edition, Anatomy for Anaesthetists provides a central pillar of anaesthetic knowledge.

Prepare yourself for success with this unique cardiology primer which distils the core information you require and presents it in an easily digestible format. Provides cardiologists with a thorough and up-to-date review of cardiology, from pathophysiology to practical, evidence-based management Ably synthesizes pathophysiology fundamentals and evidence based approaches to prepare a physician for a subspecialty career in cardiology Clinical chapters cover coronary artery disease, heart failure, arrhythmias, valvular disorders, pericardial disorders, and peripheral arterial disease Practical chapters address ECG, coronary angiography, catheterization techniques, ecnocardiography, hemodynamics, and electrophysiological testing Includes over 650 figures, key notes boxes, references for further study, and coverage of clinical trials Review questions at the end of each chapter help clarify topics and can be used for Board preparation – over 375 questions in all!

Recent years have seen extensive research in the molecular underpinnings of symbiotic plant-fungal interactions. Molecular Mycorrhizal Symbiosis is a timely collection of work that will bridge the gap between molecular biology, fungal genomics, and ecology. A more profound understanding of mycorrhizal symbiosis will have broad-ranging impacts on the fields of plant biology, mycology, crop science, and ecology. Molecular Mycorrhizal Symbiosis will open with introductory chapters on the biology, structure and phylogeny of the major types of mycorrhizal symbioses. Chapters then review different molecular mechanisms driving the development and functioning of mycorrhizal systems and molecular analysis of mycorrhizal populations and communities. The book closes with chapters that provide an overall synthesis of field and provide perspectives for future research. Authoritative and timely, Molecular Mycorrhizal Symbiosis, will be an essential reference from those working in plant and fungal biology.

Clinical Paediatric Dietetics is a comprehensive guide to the nutritional management of a wide range of paediatric disorders. It provides key information on how conditions may benefit from nutritional support or be ameliorated or resolved by dietary intervention. Covering assessment, requirements and normal healthy eating as well as the dietetic management and nutrition support of inherited metabolic disorders and diseases of all major organ systems, it is an indispensable guide for all those involved in the nutritional treatment of children. Fully revised and updated for its fourth edition, this practical manual now includes links to useful online content and incorporates a range of case studies to place material in clinical context. Written by dietitians for dietitians and officially supported by the British Dietetic Association, Clinical Paediatric Dietetics is an indispensable resource for all healthcare practitioners caring for children.

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells. Coverae includes: the morphology and interrelationships between glial cells and neurones in different parts of the nervous systems the cellular physiology of the different kinds of glial cells the mechanisms of intra- and inter-cellular signalling in glial networks the mechanisms of glial-neuronal communications the role of glial cells in synaptic plasticity, neuronal survival and development of nervous system the cellular and molecular mechanisms of metabolic neuronal-glial interactions the role of glia in nervous system pathology, including pathology of glial cells and associated diseases – for example, multiple sclerosis, Alzheimer's, Alexander disease and Parkinson's Neuroglia oversee the birth and development of neurones, the establishment of interneuronal connections (the 'connectome'), the maintenance and removal of these inter-neuronal connections, writing of the nervous system components, adult neurogenesis, the energetics of nervous tissue, metabolism of neurotransmitters, regulation of ion composition of the interstitial space and many, many more homeostatic functions. This book primes the reader towards the notion that nervous tissue is not divided into more important and less important cells. The nervous tissue functions because of the coherent and concerted action of many different cell types, each contributing to an ultimate output. This reaches its zenith in humans, with the creation of thoughts, underlying acquisition of knowledge, its analysis and synthesis, and contemplating the Universe and our place in it. An up-to-date and fully referenced text on the most numerous cells in the human brain Detailed coverage of the morphology and interrelationships between glial cells and neurones in different parts of the nervous system Describes the role og glial cells in neuropathology Focus boxes highlight key points and summarise important facts Companion website with downloadable figures and slides

Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A leader in the field and one of the pioneers of this young discipline has assembled here the most prominent experts from across the world to provide first-hand knowledge. While most of their methods and examples come from the area of pharmaceutical discovery and development, the approaches are equally applicable for chemical probes and diagnostics, pesticides, and any other molecule designed to interact with a biological system. Numerous images and screenshots illustrate the many examples and method descriptions. With its broad and balanced coverage, this will be the firststop resource not only for medicinal chemists, biochemists and biotechnologists, but equally for bioinformaticians and molecular designers for many years to come. From the content: * Reaction-driven de novo design * Adaptive methods in molecular design * Design of ligands against multitarget profiles * Free energy methods in ligand design * Fragment-based de novo design * Automated design of focused and target family-oriented compound libraries * Molecular de novo design by nature-inspired computing * 3D QSAR approaches to de novo drug design * Bioisosteres in de novo design * De novo design of peptides, proteins and nucleic acid structures, including RNA aptamers and many more.

Colorectal Cancer: Diagnosis and Clinical Management provides colorectal surgeons, gastroenterologists and oncologists with an authoritative, practical guide to best practice in the diagnosis and clinical management of colorectal cancer. Covering all forms of treatment including surgery, chemotherapy and radiotherapy, it examines the various new and emerging therapies, new strategies for screening and prevention, as well as the latest guidance on the most challenging and controversial aspects of managing colorectal cancer. The authors present important information on: Controversies in adjuvant chemotherapy Long versus short course radiotherapy Minimally invasive surgery and robotics Radical colonic resection Each chapter contains key points, tips and tricks and clinical case studies to aid rapid browsing and knowledge of the basic principles, while self-assessment questions allow readers to test their clinical knowledge. With leading international surgeons, gastroenterologists and oncologists combining to offer their considerable wealth of expertise and knowledge, Colorectal Cancer is a well-balanced, indispensable resource for all those involved in colorectal cancer management.