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Social factors have a powerful influence on human health and longevity. Yet the social dimensions of health are often obscured in public discussions due to the overwhelming focus in health policy on medical care, individual-level risk factor research, and changing individual behaviours. Likewise, in philosophical approaches to health and social justice, the debates have largely focused on rationing problems in health care and on personal responsibility. However, a range of events over the past two decades such as the study of modern famines, the global experience of HIV/AIDS, the international women’s health movement, and the flourishing of social epidemiological research have drawn attention to the robust relationship between health and broad social arrangements. In Health Justice, Sridhar Venkatapuram takes up the problem of identifying what claims individuals have in regard to their health in modern societies and the globalized world. Recognizing the social bases of health and longevity, Venkatapuram extends the ‘Capabilities Approach’ of Amartya Sen and Martha Nussbaum into the domain of health and health sciences. In so doing, he formulates an inter-disciplinary argument that draws on the natural and social sciences as well as debates around social justice to argue for every human being’s moral entitlement to a capability to be healthy. An ambitious integration of the health sciences and the Capabilities Approach, Health Justice aims to provide a concrete ethical grounding for the human right to health, while advancing the field of health policy and placing health at the centre of social justice theory. With a foreword by Sir Michael Marmot, chair of the WHO Commission on the Social Determinants of Health.

DNA typing of non-human DNA is a fast developing area of research and professional practice. The application of DNA typing in wildlife forensic science is one of these prime uses of DNA typing and is gaining increasing profile. The use of DNA profiling in wildlife forensic science falls into two broad areas: species testing and genetic linkage. Species testing answers the question ‘what species is this?’ and genetic linkage answers the question ‘did these two samples come from the same organism or population?’ Wildlife DNA Analysis: Applications in Forensic Science provides an accessible introduction to both of these key areas. Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements. •An accessible introduction to this fast developing area of research within forensic science •Case studies throughout to link theory and practice and to highlight the use of DNA testing in species testing. •Covers both crimes against wildlife and offences where wildlife can provide vital evidence •Assumes only a basic background knowledge of DNA •Includes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons

Cluster randomised trials are trials in which groups (or clusters) of individuals are randomly allocated to different forms of treatment. In health care, these trials often compare different ways of managing a disease or promoting healthy living, in contrast to conventional randomised trials which randomise individuals to different treatments, classically comparing new drugs with a placebo. They are increasingly common in health services research. This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interventions. Key features: Guides readers through the stages of conducting a trial, from recruitment to reporting. Presents a wide range of examples with particular emphasis on trials in health services research and primary care, with both principles and techniques explained. Topics are specifically presented in the order in which investigators think about issues when they are designing a trial. Combines information on the latest developments in the field together with a practical guide to the design and implementation of cluster randomised trials. Explains principles and techniques through numerous examples including many from the authors own experience. Includes a wide range of references for those who wish to read further. This book is intended as a practical guide, written for researchers from the health professions including doctors, psychologists, and allied health professionals, as well as statisticians involved in the design, execution, analysis and reporting of cluster randomised trials. Those with a more general interest will find the plentiful examples illuminating.

This well-established book gives clear guidance on normal development and how to diagnose and manage illness in newborn infants and babies. The sixth edition of the ABC of the First Year has been fully revised and updated to reflect the introduction of National Institute for Health and Clinical Excellence guidelines, the reduction in universal screening and the increasing care of the newborn provided by family practitioners and midwives. There are new sections on the recognition and prevention of obesity, which is an increasing problem. The reduction in universal screening has resulted in parents requesting advice about their child's development at a variety of ages. A Development Chart shows the age-related normal range in different abilities and activities and will enable family doctors, at a glance, to determine whether a parent should be reassured that an infant is normal or needs further assessment. The inclusion of useful links and addresses of resources and organisations helps make the new edition of the ABC of the First Year an invaluable resource for GPs, midwives, paediatric nurses, health visitors and medical students, and an ideal companion to Bernard Valman's ABC of One to Seven.

Writing for Publication in Nursing and Healthcare is an invaluable guide to ‘getting it right', focusing on all aspects of writing for publication. It will help the reader to develop skills in writing articles, book reviews and other forms of publications, and can also be used as an aide-mémoire for editors and journal or book reviewers. It explores: How to get started How to write various forms of publication including abstracts, papers, book reviews, journal articles and books Good practice in reviewing The editorial process Ethical and legal aspects of publishing Offering guidance, tips, examples and activities, this practical how-to book written by experts in the field is essential reading for all nurses and healthcare professionals.

Soft tissue tumors (STTs) are frequently misdiagnosed in inexperienced hands. Having diagnosed and treated hundreds of patients with these difficult tumors in the last few years, Institut Curie physicians have collected core data contributing to breakthrough research into the morphological, biological, and molecular aspects of soft tissue tumors, resulting in valuable translational and clinical applications to patient treatment. Soft Tissue Tumors: A Multidisciplinary, Decisional Diagnostic Approach presents a distillation of these experiences, combined with valuable data and perspectives contributed by senior pathologists, oncologists, and radiologists from several of the world’s other leading cancer centers of excellence.

This book summarizes the latest developments in key areas of the fast moving field of abdominal organ transplantation. It covers such vital topics as living donation (both renal and liver), laparoscopic and robotic techniques, islet and pancreas transplantation, non-heart beating transplantation, blood group incompatible and highly sensitized transplantation, high risk transplants, tolerance, stem cell therapy and novel immunosuppressive techniques. Each chapter offers an overview of the available evidence by a world renowned expert, written in an accessible, easy-to-read manner.

This book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The third section contains a single chapter presenting an in depth discussion of validation considerations and regulatory compliance issues associated with drug development.

This is an essential, accessible introduction to the practicalities of research and evidence-based practice aimed at all pre-registration nursing and healthcare students. It places research and evidence in the context of clinical practice, introduces the main methodological approaches in qualitative and quantitative research, and describes the processes of research appraisal, dissemination and implementation. The new edition of Research for Evidence-Based Practice in Healthcare has been updated to include information for a broader health care audience. It engages students with the research and evidence agenda, demonstrates the relevance of research and evidence to nursing practice, and provides the skills needed to explore these areas in greater detail. Special features: · A practical guide to research methods and evidence-based practice · New edition of a successful student textbook · Includes a glossary of common research terms · Provides case studies, key points, further reading, and activities throughout · Accompanying website with links to further reading

A unique textbook in cardiovascular emergencies Cardiovascular Problems in Emergency Medicine takes you on rounds with the leading teachers of emergency medicine. Transcripts of in-depth telephone conferences on 27 real-life cardiovascular cases provide a unique and fascinating insight into the way complex cases are diagnosed and managed by some of the most experienced and respected practitioners in the field. Each chapter is then complemented by an authoritative, fully-referenced review of the current literature on the topic. With its unique approach, and the range of cases covered, Cardiovascular Problems in Emergency Medicine is an invaluable source of information for all emergency physicians, both qualified and in training.

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the «bench to bedside» translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from diverse therapeutic fields, and the lessons to be learned from them, while the final part looks at new targets and opportunities, discussing several drug targets and diseases for which peptide drugs are currently being developed.

This is the definitive reference for the small animal practitioner to normal radiographic anatomy of the cat and dog. With over forty years of experience between them, the authors have produced an invaluable reference atlas for the veterinary practitioner. The book is suitable for the general and referral based practitioner, undergraduate or postgraduate veterinary surgeon. Over 550 radiographic images analysed and explained More than 50 new figures added, with the quality of existing images enhanced Revised contents and page headers for easy-reference Clear informative line drawings to trace radiographic shadows and schematic drawings of underlying structures not seen in plain radiographs.