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Vital Notes for Nurses: Psychology provides a concise, accessible introduction to key psychological theories and outlines their relevance to nursing practice. Divided into seven chapters, the first offers a preliminary insight into the different perspectives in psychology: Biological, Psychodynamic, Behavioural, Cognitive and Humanistic. These perspectives go on to underpin the topics in all the other chapters. Vital Notes for Nurses: Psychology explores developmental theories, attachment theories, and relationship theories. It discusses issues relevant to nursing practice such as motivation, change, stereotypes, relationships and motivation and looks at issues of suffering, including stress and pain. Illustrated with examples from all branches of nursing practice, this text clearly illustrates the relevance of psychology to nurses. Relates psychological themes specifically to nursing practice Written in a clear, accessible style which assumes no prior knowledge Useful to all nursing students on the common foundation programme as well as newly qualified nurses. Each chapter includes features such as activities, case studies and learning objectives

Vital Notes for Nurses: Promoting Health is a concise, accessible introduction to health promotion and public health for pre-registration nursing students and newly qualified nurses. Promoting the health and well-being of patients is a vital part of the nursing role. This introductory text in the Vital Notes for Nurses series explores issues such as public health priorities, health inequalities, health promotion settings, and the role of the nurse in health promotion roles. Written in a clear, accessible style which assumes no prior knowledge Each chapter includes learning objectives, case studies, scenarios, activities and learning outcomes Includes specific application to nursing practice in every chapter Identifies strategies for promoting health with individuals and communities and for protecting the health of the general population

Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts – giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products – evaluating cleansing and moisturising products; Adornment – looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging – ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.

Every five years, hepatologists with an interest in portal hypertension (high blood pressure in the portal vein), gather in Baveno, Italy, for the Baveno International Consensus Workshop on Portal Hypertension, attending workshops and examining the latest in clinical data and research on this condition. This book documents the contents of the meeting so that practitioners who could not be present at the conference still have access to the proceedings.

The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn these new techniques, its applications are severely limited. Describing the principles, methods, and applications of PBPK modeling as used in pharmaceutics, Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations fills this void. Connecting theory with practice, the book explores the incredible potential of PBPK modeling for improving drug discovery and development. Comprised of two parts, the book first provides a detailed and systematic treatment of the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics. The second part looks in greater detail at the powerful applications of PBPK to drug research. Designed for a wide audience encompassing readers looking for a brief overview of the field as well as those who need more detail, the book includes a range of important learning aids. Featuring end-of-chapter keywords for easy reference—a valuable asset for general or novice readers without a PBPK background—along with an extensive bibliography for those looking for further information, Physiologically- Based Pharmacokinetic (PBPK) Modeling and Simulations is the essential single-volume text on one of the hottest topics in the pharmaceutical sciences today.

This comprehensive text integrates related aspects of wound management, skin integrity and dermatology into a convenient, one-stop resource. It explores the theories underpinning wound management and skin integrity by reviewing the supporting evidence and making practical recommendations for busy clinicians. Wound Healing and Skin Integrity discusses current and future trends in the management of wounds and maintenance of skin integrity in respect to international healthcare initiatives and summarises the principles of maintaining healthy skin to provide a practical guide that is accessible to clinicians regardless of professional background. The title fulfils the inter-professional learning agenda and will be of interest to a wide range of clinicians, including doctors; wound management, dermatology and palliative care nurse specialists; community nurses; podiatrists; pharmacists; and anyone responsible for managing patients with impaired skin integrity. Key features: A practical, accessible, evidence-based manual on wound care and skin integrity Integrates related aspects of skin integrity, wound management and dermatology previously found in separate texts into one comprehensive resource Written from a broad international perspective with contributions from key international opinion leaders from Australia, UK, Canada and Europe Promotes international practice development in relation to management of skin integrity and chronic wounds Full colour illustrations throughout Defines key terms, relates anatomy and physiology to clinical practice and provides a summary of easily accessible online learning resources Includes practical tips from expert practitioners, commonly presented clinical queries and discussion of professional issues related to skin integrity

Stillbirth remains a major and tragic obstetric complication The number of deaths due to stillbirth are greater than those due to preterm birth and sudden infant death syndrome combined. Stillbirth: Prediction, Prevention and Management provides a comprehensive guide to the topic of stillbirth. Distilling recent groundbreaking research, expert authors consider: The epidemiology of stillbirth throughout the world The various possible causes of stillbirth The psychological effects on mothers and families who suffer a stillbirth Management of stillbirth Managing pregnancies following stillbirth Stillbirth: Prediction, Prevention and Management is packed with crucial evidence-based information and practical insights. It enables all obstetric healthcare providers to manage one of the most traumatic yet all too common situations they will encounter.

The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body, these pharmaceuticals can cause the immune system to produce anti-drug antibodies (ADAs) that neutralize their effects. The first and only book to cover neutralization in connection with biopharmaceuticals and the measurement and application of neutralizing antibodies in modern medicine at any real length, Detection and Quantification of Antibodies to Biopharmaceuticals: Practical and Applied Considerations offers a comprehensive and in-depth look at all the principal aspects of the detection and quantification of antibodies that are essential to understanding and responding to the challenges they present. Bringing together a large-scale review of neutralization and biopharmaceuticals and the ability to measure, detect, and apply antibodies to modern science and medicine with international regulatory perspectives, the expectations of regulatory authorities, and the strengths and weaknesses of various assays, the book describes several novel ideas for detecting ADAs. Designed to serve as a resource for biopharmaceutical drug development, the book provides biotechnology companies and pharmaceutical drug development specialists, as well as non-experts, with key insights into the design, optimization, and qualification of assays, the establishment of sampling strategies, the choice of appropriate assay end-points, and data analysis for the detection and quantification of neutralizing antibodies.

Health Care in the United States combines an explanation of population health with a comprehensive introduction to health services delivery. The author, an expert on health care policy and management, shows how the U.S. health services system is organized, managed, financed, and evaluated. Filled with numerous examples and tables, this important resource illustrates key concepts, trends, and features of the system. It places special emphasis on recent health care reform legislation and its implications for the future. Health Care in the United States reviews the historical origins of health care, its resource requirements, costs, quality, and contributions to both individual and social well-being. By combining basic concepts in population health with coverage of health services, the book offers extraordinary breadth of information in a highly accessible, easy-to-read text. Along with an in-depth look at the origins and possible impact of recent health reform legislation, the book explains the ongoing dilemmas that face the health care system and highlights health and disease in the modern world, the fundamentals of epidemiology, and health behavior. Health Care in the United States also explains the special challenges of managing health service personnel and organizations. The author reviews key innovations in financing and delivery, explaining the outcomes of cost sharing, HMO enrollment, and rationing of services. This vital resource is written for students and professionals in health care management and policy, as well as public health, medical sociology, medical anthropology, social work, political science, and most, if not all, clinical fields.

American health care has made great strides in the past hundred years. Life expectancy has increased dramatically and advances in medicine and treatments have eradicated many life-threatening diseases. However, in today's health care arena there is divergence between our health needs, the structure of our health care system, and how health care is delivered and funded. In Forces of Change, David A. Shore has collected the leading thinking from experts in the field on how our health care system can benefit from important lessons from other industries and effect transformational change that truly serves all stakeholders well. Contributors include Max Caldwell of Towers Watson; Michael J. Dowling of North Shore–Long Island Jewish Medical Health System; John P. Glaser of Siemens Healthcare; Ashish K. Jha of the Harvard School of Public Health; Eric D. Kupferberg of Northeastern University; Lucian Leape of the Harvard School of Public Health; Jeff Margolis of the TriZetto Group, Inc.; and David Shoultz of Philips Electronics.

Ethical medical practice and treatment in psychiatry are based on the concept of first do no harm. However, this cannot, and does not, apply to forensic cases where there is no doctor–patient relationship and the forensic psychiatrist may indeed cause harm to the examinee. In this book, Robert Sadoff analyzes the ethical issues affecting forensic psychiatric practice, especially those promulgated by the American Academy of Psychiatry and the Law. Within those guidelines, he looks at individual bias, vulnerability of the examinee, and potential harm to the mental health professional. The book discusses each of the procedures of the forensic expert separately with respect to minimizing harm. It has been written with an international audience in mind and features chapters reviewing the European and UK perspectives, by Emanuele Valenti and John Baird, respectively. Robert Sadoff addresses the long-term harm that can be either avoided or minimized through careful planning and application of ethical principles. He is not advocating that the harm can be totally eliminated, because that is impossible in the adversarial system in which forensic psychiatrists work. However, there are means by which harm may be minimized if care is taken during the assessment, the report writing, and the testimony phase of the proceedings. The book develops the scope of forensic psychiatry from the standpoint of administrative, civil and criminal cases. It presents the practical issues involved in conducting forensic psychiatric assessments under various conditions plus special considerations, such as bias, minimizing harm, developing a therapeutic approach, and elaborating on various vulnerable individuals who are frequently examined in forensic cases. These include juveniles, mentally retarded, autistic, sexual assault victims, the elderly, the organically damaged, the psychotic, and mentally disabled prisoners. Immigrants are covered in a chapter by Solange Margery Bertoglia. The ethical issues in conducting forensic psychiatric examinations and presenting psychiatric testimony in court are examined and discussed. Cases illustrating the difficulties involved punctuate the presentation. The book closes with a fascinating account of the legal perspective by Donna Vanderpool. In summary, this book illustrates the ethical and practical issues that affect forensic psychiatric practice. The question is not what we do, but how we do it, and which standards, ethical guidelines and personal values contribute to the total picture. Despite the fact that we cannot always adhere to the doctrine of «primum non nocere,» we can minimize the harm caused inherently by the adversarial system in which we participate. Praise for Ethical Issues in Forensic Psychiatry «One of the founding giants of the forensic psychiatric field has written here far more than a „mere“ ethics textbook. Instead, this compendium serves multiple purposes: it is a valuable primer on forensic techniques of examinati

The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the first comprehensive two-volume reference to cover unculturable microorganisms in a large variety of habitats, which could not previously have been analyzed without metagenomic methodology. It features review articles as well as a large number of case studies, based largely on original publications and written by international experts. This second volume, Metagenomics in Different Habitats, covers such topics as: Viral genomes Metagenomics studies in a variety of habitats, including marine environments and lakes, soil, and human and animal digestive tracts Other habitats, including those involving microbiome diversity in human saliva and functional intestinal metagenomics; diversity of archaea in terrestrial hot springs; and microbial communities living at the surface of building stones Biodegradation Biocatalysts and natural products A special feature of this book is the highlighting of the databases and computer programs used in each study; they are listed along with their sites in order to facilitate the computer-assisted analysis of the vast amount of data generated by metagenomic studies. Such studies in a variety of habitats are described here, which present a large number of different system-dependent approaches in greatly differing habitats. Handbook of Molecular Microbial Ecology II is an invaluable reference for researchers in metagenomics, microbial ecology, microbiology, and environmental microbiology; those working on the Human Microbiome Project; microbial geneticists; and professionals in molecular microbiology and bioinformatics.