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The first and only exhaustive review of the theory, thermodynamic fundamentals, mechanisms, and design principles of dynamic covalent systems Dynamic Covalent Chemistry: Principles, Reactions, and Applications presents a comprehensive review of the theory, thermodynamic fundamentals, mechanisms, and design principles of dynamic covalent systems. It features contributions from a team of international scientists, grouped into three main sections covering the principles of dynamic covalent chemistry, types of dynamic covalent chemical reactions, and the latest applications of dynamic covalent chemistry (DCvC) across an array of fields. The past decade has seen tremendous progress in (DCvC) research and industrial applications. The great synthetic power and reversible nature of this chemistry has enabled the development of a variety of functional molecular systems and materials for a broad range of applications in organic synthesis, materials development, nanotechnology, drug discovery, and biotechnology. Yet, until now, there have been no authoritative references devoted exclusively to this powerful synthetic tool, its current applications, and the most promising directions for future development. Dynamic Covalent Chemistry: Principles, Reactions, and Applications fills the yawning gap in the world literature with comprehensive coverage of: The energy landscape, the importance of reversibility, enthalpy vs. entropy, and reaction kinetics Single-type, multi-type, and non-covalent reactions, with a focus on the advantages and disadvantages of each reaction type Dynamic covalent assembly of discrete molecular architectures, responsive polymer synthesis, and drug discovery Important emerging applications of dynamic covalent chemistry in nanotechnology, including both material- and bio-oriented directions Real-world examples describing a wide range of industrial applications for organic synthesis, functional materials development, nanotechnology, drug delivery and more Dynamic Covalent Chemistry: Principles, Reactions, and Applications is must-reading for researchers and chemists working in dynamic covalent chemistry and supramolecular chemistry. It will also be of value to academic researchers and advanced students interested in applying the principles of (DCvC) in organic synthesis, functional materials development, nanotechnology, drug discovery, and chemical biology.

A comprehensive examination of DMPC theory and its technological applications • A comprehensive examination of DMPC theory and its technological applications from basic through to advanced level • A systematic introduction to DMPC technology providing classic DMPC coordination strategies, analysis of their performance, and design methods for both unconstraint and constraint systems • Includes the system partition methods, coordination strategies, the performance analysis and how to design stabilized DMPC under different coordination strategies • Presents useful theories and technologies which can be used in many different industrial fields, such as the metallurgical process and high speed transport, helping readers to grasp the procedure of using the DMPC • Reflects the authors’ combined research in the area, providing a wealth of and current and background information

Fundamental guidance—including concepts, models, and methodology—for better understanding the dynamic behavior of materials and for designing for objects and structures under impact or intensive dynamic loading This book introduces readers to the dynamic response of structures with important emphasis on the material behavior under dynamic loadings. It utilizes theoretical modelling and analytical methods in order to provide readers with insight into the various phenomena. The content of the book is an introduction to the fundamental aspects, which underpin many important industrial areas. These areas include the safety of various transportation systems and a range of different structures when subjected to various impact and dynamic loadings, including terrorist attacks. Presented in three parts—Stress Waves in Solids, Dynamic Behaviors of Materials Under High Strain Rate, and Dynamic Response of Structures to Impact and Pulse Loading—Introduction to Impact Dynamics covers elastic waves, rate dependent behaviors of materials, effects of tensile force, inertial effects, and more. The book also features numerous case studies to aid in facilitating learning. The strength of the book is its clarity, balanced coverage, and practical examples, which allow students to learn the overall knowledge of impact dynamics in a limited time whilst directing them to explore more advanced technical knowledge and skills. Considers both the dynamic behavior of materials and stress waves, and the dynamic structural response and energy absorption, emphasizing the interaction between material behavior and the structural response Provides a comprehensive description of the phenomenon of impact of structures, containing both fundamental issues of wave propagation and constitutive relation of materials, and the dynamic response of structures under impact loads Based on the authors’ research and teaching experience as well as updated developments in the field Introduction to Impact Dynamics is the perfect textbook for graduate and postgraduate students, and will work as a reference for engineers in the fields of solid mechanics, automotive design, aerospace, mechanical, nuclear, marine, and defense.

As one of the most important classes of soft materials, supramolecular materials are of a mixture of networks of molecular chains/fibrils and a liquid. These self-assembled fibrous/ molecular architectures exhibit various functionalities, ie. superhydrophobicity or superior mechanical strength, etc. and consist of the controllable structures. They can be functioned via micro/nano engineering, to have some particular added functions, ie. emission materials, tissue engineering scaffolds, bio imaging and sensing materials etc. They have therefore found broad applications in photography, cosmetics, food and petroleum industries and not the least in the biomedical sector where there is strong interest in these materials as drug delivery agents. The book covers the most important soft functional materials, including small molecule physical gels, silkworm silk and spider silk fibers and functional fibers, with respect both to the fundamentals and to development and engineering methods. It provides the reader with the necessary knowledge on the chemical and physical formation mechanisms of these materials and demonstrates that one can rationally design and tune the fibrillar networks so that the resulting materials exhibit the desired functionalities. This work is a must-have for all Materials Scientists, Polymer Chemists, Condensed Matter Physicists, and Biotechnologists working in this interdisciplinary field.

The beginning of the new millennium has been particularly devastating in terms of natural disasters associated with tectonic plate boundaries, such as earthquakes in Sumatra, Chile, Japan, Tahiti, and Nepal; the Indian Ocean and the Pacific Ocean tsunamis; and volcanoes in Indonesia, Chile, Iceland that have produced large quantities of ash causing major disruption to aviation. In total, half a million people were killed by such natural disasters. These recurring events have increased our awareness of the destructive power of natural hazards and the major risks associated with them. While we have come a long way in the search for understanding such natural phenomena, and although our knowledge of Earth dynamics and plate tectonics has improved enormously, there are still fundamental uncertainties in our understanding of natural hazards. Increased understanding is crucial to improve our capacity for hazard prediction and mitigation. Volume highlights include: Main concepts associated with tectonic plate boundaries Novel studies on boundary-related natural hazards Fundamental concepts that improve hazard prediction and mitigation Plate Boundaries and Natural Hazards will be a valuable resource for scientists and students in the fields of geophysics, geochemistry, plate tectonics, natural hazards, and climate science.

Providing an eclectic snapshot of the current state of the art and future implications of the field, Nanomaterials, Polymers, and Devices: Materials Functionalization and Device Fabrication presents topics grouped into three categorical focuses: The synthesis, mechanism and functionalization of nanomaterials, such as carbon nanotubes, graphene, silica, and quantum dots Various functional devices which properties and structures are tailored with emphasis on nanofabrication. Among discussed are light emitting diodes, nanophotonic, nano-optical, and photovoltaic devices Nanoelectronic devices, which include semiconductor, nanotube and nanowire-based electronics, single-walled carbon-nanotube based nanoelectronics, as well as thin-film transistors

The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics research Analytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for increasingly complex molecular designs, the book explores the history of the analysis techniques and offers valuable insights into the most important emerging analytical solutions. In addition, it frames critical questions warranting attention in the design and delivery of a therapeutic protein, exposes analytical challenges that may occur when characterizing these molecules, and presents a number of tested solutions. The first single-volume guide of its kind, Analytical Characterization of Biotherapeutics brings together contributions from scientists at the leading edge of biotherapeutics research and manufacturing. Key topics covered in-depth include the structural characterization of recombinant proteins and antibodies, antibody de novo sequencing, characterization of antibody drug conjugates, characterization of bi-specific or other hybrid molecules, characterization of manufacturing host-cell contaminant proteins, analytical tools for biologics molecular assessment, and more. Each chapter is written by a recognized expert or experts in their field who discuss current and cutting edge approaches to fully characterizing biotherapeutic proteins and antigen reagents Covers the full range of characterization strategies for large molecule based therapeutics Provides an up-to-date account of the latest approaches used for large molecule characterization Chapters cover the background needed to understand the challenges at hand, solutions to characterize these large molecules, and a summary of emerging options for analytical characterization Analytical Characterization of Biotherapeutics is an up-to-date resource for analytical scientists, biologists, and mass spectrometrists involved in the analysis of biomolecules, as well as scientists employed in the pharmaceuticals and biotechnology industries. Graduate students in biology and analytical science, and their instructors will find it to be fascinating and instructive supplementary reading.

Presents current research into electromagnetic computation theories with particular emphasis on Finite-Difference Time-Domain Method This book is the first to consolidate current research and to examine the theories of electromagnetic computation methods in relation to lightning surge protection. The authors introduce and compare existing electromagnetic computation methods such as the method of moments (MOM), the partial element equivalent circuit (PEEC), the finite element method (FEM), the transmission-line modeling (TLM) method, and the finite-difference time-domain (FDTD) method. The application of FDTD method to lightning protection studies is a topic that has matured through many practical applications in the past decade, and the authors explain the derivation of Maxwell’s equations required by the FDTD, and modeling of various electrical components needed in computing lightning electromagnetic fields and surges with the FDTD method. The book describes the application of FDTD method to current and emerging problems of lightning surge protection of continuously more complex installations, particularly in critical infrastructures of energy and information, such as overhead power lines, air-insulated sub-stations, wind turbine generator towers and telecommunication towers. Both authors are internationally recognized experts in the area of lightning study and this is the first book to present current research in lightning surge protection Examines in detail why lightning surges occur and what can be done to protect against them Includes theories of electromagnetic computation methods and many examples of their application Accompanied by a sample printed program based on the finite-difference time-domain (FDTD) method written in C++ program

By focusing on the cellular mechanisms that underlie ontogeny, phylogeny and regeneration of complex physiologic traits, Evolution, the Logic of Biology demonstrates the use of homeostasis, the fundamental principle of physiology and medicine, as the unifying mechanism for evolution as all of biology. The homeostasis principle can be used to understand how environmental stressors have affected physiologic mechanisms to generate condition-specific novelty through cellular mechanisms. Evolution, the Logic of Biology allows the reader to understand the vertebrate life-cycle as an intergenerational continuum in support of effective, on-going environmental adaptation. By understanding the principles of physiology from their fundamental unicellular origins, culminating in modern-day metazoans, the reader as student, researcher or practitioner will be encouraged to think in terms of the prevention of disease, rather than in the treatment of disease as the eradication of symptoms. By tracing the ontogeny and phylogeny of this and other phenotypic homologies, one can perceive and understand how complex physiologic traits have mechanistically evolved from their simpler ancestral and developmental origins as cellular structures and functions, providing a logic of biology for the first time. Evolution, the Logic of Biology will be an invaluable resource for graduate students and researchers studying evolutionary development, medicine and biology, anthropology, comparative and developmental biology, genetics and genomics, and physiology.

Provides corrosion basics in a lucid manner to students and working professionals and over 80 corrosion-failure analysis case studies Correlates Failure Analysis with Corrosion Science Exclusively provides corrosion-related failure analysis case histories in one place in a convenient format One-stop shop for both science and real time occurrence of the phenomenon of corrosion Full coverage of all MOC, Materials of Construction, used for process equipments Simple but Lucid presentation of Failure Analysis procedure

The International System of Units (SI) is the world's most widely used system of measurement, used every day in commerce and science, and is the modern form of the metric system. It currently comprises the meter (m), the kilogram (kg), the second (s), the ampere (A), the kelvin (K), the candela (cd) and the mole (mol)). The system is changing though, units and unit definitions are modified through international agreements as the technology of measurement progresses, and as the precision of measurements improves. The SI is now being redefined based on constants of nature and their realization by quantum standards. Therefore, the underlying physics and technologies will receive increasing interest, and not only in the metrology community but in all fields of science. This book introduces and explains the applications of modern physics concepts to metrology, the science and the applications of measurements. A special focus is made on the use of quantum standards for the realization of the forthcoming new SI (the international system of units). The basic physical phenomena are introduced on a level which provides comprehensive information for the experienced reader but also provides a guide for a more intense study of these phenomena for students.

Written with both postgraduate students and researchers in academia and industry in mind, this reference covers the chemistry behind metal nanopowders, including production, characterization, oxidation and combustion. The contributions from renowned international scientists working in the field detail applications in technologies, scale-up processes and safety aspects surrounding their handling and storage.