Медицина - скачать книги или читать онлайн. Страница 112

Mindfulness: A Kindly Approach to Being with Cancer offers people with cancer a means to bring mindfulness and kindliness into their lives, to help them cope with the challenge of a life-threatening illness. Adapts Mindfulness-Based Cognitive Therapy (MBCT), an approach with a strong evidence base for people with recurrent depression, for the needs and challenges of people with cancer Presents the standard 8-week course of MBCT for cancer in a flexible format that is designed to suit each reader’s own particular timescale, context and situation Based on more than 15 years of program development and clinical application by the author, and the work and experience of mindfulness teachers in other cancer centres around the world Provides specific practices and approaches tailored to support the different phases of a cancer experience – from diagnosis and treatment to living with uncertainty and managing life with cancer Features five extended stories from people personally affected by cancer who have used mindfulness-based practices to support them in their own experience of illness, life and treatment

Supra-Gingival Minimally Invasive Dentistry: A Healthier Approach to Esthetic Restorations provides a real-world approach to healthier supra-gingival minimally invasive restorations, as an alternative to more invasive mechanically retained restorations, such as full crowns. Provides practical, step-by-step coverage of the key elements in diagnosis, case planning, preparation, restorations, and cementation of bonded restorations Offers excellent and simple explanations of the latest in adhesive dentistry and the proper selection of restorative materials Covers both anterior and posterior direct and indirect bonded restorations, offering a better, healthier approach Presents hundreds of beautiful images showing planning, preparation, and restoration principles and treatment Features the contributions of Dr. Ray Bertolotti, Contributing Editor, and a foreword written by Gordon J. Christensen, DDS, MSD, PhD, CEO of Clinicians Report Foundation and Practical Clinical Reports

This newly updated edition covers a wide range of topics relevant to fungal biology, appealing to academia and industry Fungi are extremely important microorganisms in relation to human and animal wellbeing, the environment, and in industry. The latest edition of the highly successful Fungi: Biology and Applications teaches the basic information required to understand the place of fungi in the world while adding three new chapters that take the study of fungi to the next level. Due to the number of recent developments in fungal biology, expert author Kevin Kavanagh found it necessary to not only update the book as a whole, but to also provide new chapters covering Fungi as Food, Fungi and the Immune Response, and Fungi in the Environment. Proteomics and genomics are revolutionizing our understanding of fungi and their interaction with the environment and/or the host. Antifungal drug resistance is emerging as a major problem in the treatment of fungal infections. New fungal pathogens of plants are emerging as problems in temperate parts of the world due to the effect of climate change. Fungi: Biology and Applications, Third Edition offers in-depth chapter coverage of these new developments and more—ultimately exposing readers to a wider range of topics than any other existing book on the subject. Includes three new chapters, which widen the scope of fungi biology for readers Takes account of recent developments in a wide range of areas including proteomics and genomics, antifungal drug resistance, medical mycology, physiology, genetics, and plant pathology Provides extra reading at the end of each chapter to facilitate the learning process Fungi: Biology and Applications is designed for undergraduate students, researchers, and those working with fungi for the first time (postgraduates, industrial scientists).

Written for the clinician, Cone Beam Computed Tomography helps the reader understand how CBCT machines operate, perform advanced diagnosis using CT data, have a working knowledge of CBCT-related treatment planning for specific clinical tasks, and integrate these new technologies in daily practice. This comprehensive text lays the foundation of CBCT technologies, explains how to interpret the data, recognize main pathologies, and utilize CBCT for diagnosis, treatment planning, and execution. Dr. Sarment first addresses technology and principles, radiobiologic risks, and CBCT for head and neck anatomy. The bulk of the text discusses diagnosis of pathologies and uses of CBCT technology in maxillofacial surgical planning, orthodontic and orthognathic planning, implant surgical site preparation, CAD/CAM surgical guidance, surgical navigation, endodontics airway measurements, and periodontal disease.

The number-one guide, internationally, to all aspects of forensic isotope analysis, thoroughly updated and revised and featuring many new case studies This edition of the internationally acclaimed guide to forensic stable isotope analysis uses real-world examples to bridge discussions of the basic science, instrumentation and analytical techniques underlying forensic isotope profiling and its various technical applications. Case studies describe an array of applications, many of which were developed by the author himself. They include cases in which isotope profiling was used in murder, and drugs-related crime investigations, as well as for pharmaceutical and food authenticity control studies. Updated with coverage of exciting advances occurring in the field since the publication of the 1st edition, this 2nd edition explores innovative new techniques and applications in forensic isotope profiling, as well as key findings from original research. More than a simple update, though, this edition has been significantly revised in order to address serious problems that can arise from non-comparable and unfit-for-purpose stable isotope data. To that end, Part II has been virtually rewritten with greater emphasis now being placed on important quality control issues in stable isotope analysis in general and forensic stable isotope analysis in particular. Written in a highly accessible style that will appeal to practitioners, researchers and students alike Illustrates the many strengths and potential pitfalls of forensic stable isotope analysis Uses recent case examples to bridge underlying principles with technical applications Presents hands-on applications that let experienced researchers and forensic practitioners match problems with success stories Includes new chapters devoted to aspects of quality control and quality assurance, including scale normalisation, the identical treatment principle, hydrogen exchange and accreditation Stable Isotope Forensics, 2nd Edition is an important professional resource for forensic scientists, law enforcement officials, public prosecutors, defence attorneys, forensic anthropologists and others for whom isotope profiling has become an indispensable tool of the trade. It is also an excellent introduction to the field for senior undergraduate and graduate forensic science students. «All students of forensic criminology, and all law enforcement officers responsible for the investigation of serious crime , will want to study this book. Wolfram highlights the value, and future potential, of Stable Isotope Forensics as an emerging powerful tool in the investigation of crime.» —Roy McComb, Deputy Director, Specialist Investigations, National Crime Agency (NCA), UK “A single author text in these days is rare and the value of this book lies in the dedication and experience of the author which is evident in the clarity of prose, the honest illustration of evidence and the realistic practical application of the subject – it mak

With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand complex neuroscience issues. The author illustrates medicinal chemistry's prominent role in treating addiction and covers specific drugs of abuse including narcotics, stimulants, depressants, nicotine, and marijuana. • Interprets complex neuro- biological and pharmacological information, like the drug-reward system, for medicinal chemists • Emphasizes neurotransmitters and neurochemical mechanisms of addictive drugs • Pulls together information on the many potential drug targets for treating addiction • Stresses unique medicinal chemistry problems when describing pharmacology testing methods and drug development

The Cerebellum provides a concise, accessible overview of modern data on physiology and function of the cerebellum as it relates to learning, plasticity, and neurodegenerative diseases. Encompassing anatomy and physiology, theoretical work, cellular mechanisms, clinical research, and disorders, the book covers learning and plasticity while introducing the anatomy of the cerebellum. Known and proposed «functions of the cerebellum» are addressed on clinical, physiological, cellular, and computational levels, providing academics, researchers, medical students, and graduate students with an invaluable reference.

The Fourth Edition of Changing the U.S. Health Care System addresses the key topics in health care policy and management, presenting evidence-based views of current issues. Each chapter is written by an expert in the field who integrates evidence to explain the current condition and presents support for needed change. The book examines all the levers in the setting and implementation of health policy, and includes extensive coverage of impact of the Affordable Care Act, particularly on Medicare, Medicaid, and large and small group insurance markets. Also new to this edition is expanded coverage of nursing, disease management, mental health, women's health, children's health, and care for the homeless.

Forensic Ballistics in Court: Interpretation and Presentation of Firearms Evidence is an accessible introduction to firearms and ballistics evidence and how this is analysed and presented as evidence in a court of law. The book approaches the subject in terms of the realities of case work, opening with a clear and illustrated explanation of the correct nomenclature for various weapon types and their parts. Ammunition is also extensively covered, again with annotated illustrations. Basic external and terminal ballistics, wounding capabilities are likewise covered to give an overview of the subject. A key aspect of the book covers the theory and philosophy behind striation matches and the associated statistics, how positive matches should be peer reviewed and the importance accreditation has on this subject. Gunshot residue formation and identification and the various methods used in its analysis are reviewed in depth. This includes a critical examination of the pros and cons of each type of examination and the evidential weight which can be applied to each method. Accessible and reader-friendly introduction to firearms and ballistics. Clarifies the limitations of firearms evidence. Extensive use of global case-studies throughout. Focus on the interpretation and assessment of the weight of firearms/ballistics evidence presented at court. Covers the importance of witness and accused statements and their interpretation in relation to the investigation under review. Includes coverage of gunshot residue collection, examination and interpretation and the potential for contamination of GSR samples. Includes numerous real life case studies that the author has dealt with over the past 45 years. Takes an applied approach to the subject.

Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, as well as their integrated applications in the management of individual cardiovascular diseases. • Integrates fundamentals and recent advances regarding cardiovascular drugs, blending basic and clinical sciences needed to effectively understand and treat cardiovascular diseases • Facilitates understanding of drug action and mechanism by covering physiology / pathophysiology and pharmacology • Includes guidelines and algorithms for pharmacotherapeutic management of cardiovascular diseases • Uses case presentations and study questions to enhance understanding of the material • Serves as a resource for pharmaceutical and medical students and researchers interested in cardiovascular issues

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development. • Helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods • Chapters organized according to the sequential nature of the drug development process • Helps formulation, analytical, and bioanalytical scientists in pharma and biotech better understand and usestrengths and limitations of biophysical methods • Explains how to use biophysical methods, the information obtained, and what needs to be presented in a regulatory filing, assess impact on quality and immunogenicity • With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development.