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Reliable and detailed information about the Earth’s subsurface is of crucial importance throughout the geosciences. Quantitative integration of all available geophysical and geological data helps to make Earth models more robust and reliable. The aim of this book is to summarize and synthesize the growing literature on combining various types of geophysical and other geoscientific data. The approaches that have been developed to date encompass joint inversion, cooperative inversion, and statistical post-inversion analysis methods, each with different benefits and assumptions. Starting with the foundations of inverse theory, this book systematically describes the mathematical and theoretical aspects of how to best integrate different geophysical datasets with geological prior understanding and other complimentary data. This foundational basis is followed by chapters that demonstrate the diverse range of applications for which integrated methods have been used to date. These range from imaging the hydrogeological properties of the near-surface to natural resource exploration and probing the composition of the lithosphere and the deep Earth. Each chapter is written by leading experts in the field, which makes this book the definitive reference on integrated imaging of the Earth. Highlights of this volume include: Complete coverage of the theoretical foundations of integrated imaging approaches from inverse theory to different coupling methods and quantitative evaluation of the resulting models Comprehensive overview of current applications of integrated imaging including hydrological investigations, natural resource exploration, and imaging the deep Earth Detailed case studies of integrated approaches providing valuable guidance for both experienced users and researchers new to joint inversion. This volume will be a valuable resource for graduate students, academics, industry practitioners, and researchers who are interested in using or developing integrated imaging approaches.

Mechanical behaviors of materials are highly influenced by their architectures and/or microstructures. Hence, progress in material science involves understanding and modeling the link between the microstructure and the material behavior at different scales. This book gathers contributions from eminent researchers in the field of computational and experimental material modeling. It presents advanced experimental techniques to acquire the microstructure features together with dedicated numerical and analytical tools to take into account the randomness of the micro-structure.

Theory and Application of Multiphase Lattice Boltzmann Methods presents a comprehensive review of all popular multiphase Lattice Boltzmann Methods developed thus far and is aimed at researchers and practitioners within relevant Earth Science disciplines as well as Petroleum, Chemical, Mechanical and Geological Engineering. Clearly structured throughout, this book will be an invaluable reference on the current state of all popular multiphase Lattice Boltzmann Methods (LBMs). The advantages and disadvantages of each model are presented in an accessible manner to enable the reader to choose the model most suitable for the problems they are interested in. The book is targeted at graduate students and researchers who plan to investigate multiphase flows using LBMs. Throughout the text most of the popular multiphase LBMs are analyzed both theoretically and through numerical simulation. The authors present many of the mathematical derivations of the models in greater detail than is currently found in the existing literature. The approach to understanding and classifying the various models is principally based on simulation compared against analytical and observational results and discovery of undesirable terms in the derived macroscopic equations and sometimes their correction. A repository of FORTRAN codes for multiphase LBM models is also provided.

This volume will be summarized on the basis of the topics of Ionic Liquids in the form of chapters and sections. It would be emphasized on the synthesis of ILs of different types, and stabilization of amphiphilic self-assemblies in conventional and newly developed ILs to reveal formulation, physicochemical properties, microstructures, internal dynamics, thermodynamics as well as new possible applications. It covers: Topics of ionic liquid assisted micelles and microemulsions in relation to their fundamental characteristics and theories Development bio-ionic liquids or greener, environment-friendly solvents, and manifold interesting and promising applications of ionic liquid based micelles and micremulsions

The book focuses on advanced characterization methods for thin-film solar cells that have proven their relevance both for academic and corporate photovoltaic research and development. After an introduction to thin-film photovoltaics, highly experienced experts report on device and materials characterization methods such as electroluminescence analysis, capacitance spectroscopy, and various microscopy methods. In the final part of the book simulation techniques are presented which are used for ab-initio calculations of relevant semiconductors and for device simulations in 1D, 2D and 3D. Building on a proven concept, this new edition also covers thermography, transient optoelectronic methods, and absorption and photocurrent spectroscopy.

Providing a modern update of the field, Mossbauer Spectroscopy focuses on applications across a broad range of fields, including analysis of inorganic elements, nanoparticles, metalloenzymyes, biomolecules (including proteins), glass, coal, and iron. Ideal for a broad range of scientists, this one-stop reference presents advances gained in the field over past two decades, including a detailed theoretical description of Mossbauer spectroscopy, an extensive treatment of Mossbauer spectroscopy in applied areas, and challenges and future opportunities for the further development of this technique.

Fluoropolymers continue to enable new materials and technologies as a result of their remarkable properties. This book reviews fluoropolymer platforms of established commercial interest, as well as recently discovered methods for the preparation and processing of new fluorinated materials. It covers the research and development of fluoropolymer synthesis, characterization, and processing. Emphasis is placed on emerging technologies in optics, space exploration, fuel cells, microelectronics, gas separation membranes, biomedical instrumentation, and much more. In addition, the book covers the current environmental concerns associated with fluoropolymers, as well as relevant regulations and potential growth opportunities. Concepts, studies, and new discoveries are taken from leading international laboratories, including academia, government, and industrial institutions.

Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product. The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry. Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scientists involved in product and process development, as well as teachers, on how to utilize QbD practices and applications effectively while complying with government regulations. The material is divided into three main sections: the first six chapters address the role of key technologies, including process modeling, process analytical technology, automated process control and statistical methodology in supporting QbD and establishing the associated design space. The second section consisting of seven chapters present a range of thoroughly developed case studies in which the tools and methodologies discussed in the first section are used to support specific drug substance and drug-product QbD related developments. The last section discussed the needs for integrated tools and reviews the status of information technology tools available for systematic data and knowledge management to support QbD and related activities. Highlights Demonstrates Quality by Design (QbD) concepts through concrete detailed industrial case studies involving of the use of best practices and assessment of regulatory implications Chapters are devoted to applications of QbD methodology in three main processing sectors—drug substance process development, oral drug product manufacture, parenteral product processing, and solid-liquid processing Reviews the spectrum of process model types and their relevance, the range of state-of-the-art real-time monitoring tools and chemometrics, and alternative automatic process control strategies and methods for both batch and continuous processes The role of the design space is demonstrated through specific examples and the importance of understanding the risk management aspects of design space definition is highlighted Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture is an ideal book for practitioners, researchers, and graduate students involved in the development, research, or studying of a new drug and its associated manufacturing process.

Over the past decade, renewables-based technology and sustainability assessment methods have grown tremendously. Renewable energy and products have a significant role in the market today, and the same time sustainability assessment methods have advanced, with a growing standardization of environmental sustainability metrics and consideration of social issues as part of the assessment. Sustainability Assessment of Renewables-Based Products: Methods and Case Studies is an extensive update and sequel to the 2006 title Renewables-Based Technology: Sustainability Assessment. It discusses the impressive evolution and role renewables have taken in our modern society, highlighting the importance of sustainability principles in the design phase of renewable-based technologies, and presenting a wide range of sustainability assessment methods suitable for renewables-based technologies, together with case studies to demonstrate their applications. This book is a valuable resource for academics, businesses and policy makers who are active in contributing to more sustainable production and consumption. For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs Topics covered include: The growing role of renewables in our society Sustainability in the design phase of products and processes Principles of sustainability assessment Land use analysis Water use analysis Material and energy flow analysis Exergy and cumulative exergy analysisCarbon and environmental footprint methods Life Cycle Assessment (LCA), social Life Cycle Assessment and Life Cycle Costing (LCC) Case studies: renewable energy, bio-based chemicals and bio-based materials.

Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

The workbook that helps students connect emotional intelligence with leadership skills The Emotionally Intelligent Leadership for Students: Student Workbook contains hands-on activities and case studies to help students foster the 19 capacities of emotionally intelligent leadership (EIL) presented in the main text Emotionally Intelligent Leadership: A Guide for Students. Research from around the world has demonstrated that there is a relationship between emotional intelligence and leadership. For the substantially revised second edition, the authors have completely rewritten all modules and activities according to their data-based model. These activities bring theory into practice, targeting specific learning outcomes that will help students become better leaders. The workbook can be used in conjunction with the Emotionally Intelligent Leadership for Students: Inventory which helps students to assess their leadership behaviors. The companion Emotionally Intelligent Leadership for Students: Facilitation and Activity Guide is aligned with the workbook to serve as a road map for educators. Contains 23 all new modules consisting of activities and case studies that further the understanding and relevancy of the emotionally intelligent leadership model Reflects 19 emotionally intelligent leadership capacities derived from new research research that provides evidence of construct validity Can be used as a self-guided experience for developing capacities of EIL Includes tips for improving each leadership capacity, suggestions for further reading, and films to watch The Emotionally Intelligent Leadership for Students suite of resources offers an immersive and transformative educational experience, fostering growth and promoting intense self-reflection. Students will be empowered to develop into the effective leaders of the future.

Provides a review of novel pharmaceutical approaches for Tuberculosis drugs Presents a novel perspective on tuberculosis prevention and treatment Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering