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Enhancing Human Capacities is the first to review the very latest scientific developments in human enhancement. It is unique in its examination of the ethical and policy implications of these technologies from a broad range of perspectives. Presents a rich range of perspectives on enhancement from world leading ethicists and scientists from Europe and North America The most comprehensive volume yet on the science and ethics of human enhancement Unique in providing a detailed overview of current and expected scientific advances in this area Discusses both general conceptual and ethical issues and concrete questions of policy Includes sections covering all major forms of enhancement: cognitive, affective, physical, and life extension

Accurate, high-quality images are especially vital for gastrointestinal therapy. The Atlas of Gastroenterology is a gold-standard tool that provides specialists with an outstanding array of images covering all facets of the field. With endoscopic ultrasonographs, computed tomography scans, magnetic resonance images, radionuclide images, and angiograms demonstrating every clinical condition from liver abscess, to endocrine neoplasms of the pancreas, to motility disorders of the esophagus, this atlas is simply a must-own resource for all gastroenterologists. Showing the range of the newest imaging technologies and incorporating over 1700 full-color images, this new edition is an ideal teaching tool, and the perfect companion to the Textbook of Gastroenterology.

Cardiac Resynchronization Therapy continues to evolve at a rapid pace. Growing clinical experience and additional clinical trials are resulting in changes in how patients are selected for CRT. This new edition of the successful Cardiac Resynchronization Therapy builds on the strengths of the first edition, providing basic knowledge as well as an up-to-date summary of new advances in CRT for heart failure. Fully updated to include information on technological advances, trouble shooting and recent key clinical trials, and with nine new chapters, this expanded text provides the latest information, keeping the reader up-to-date with this rapidly evolving field. The second edition of Cardiac Resynchronization Therapy is an essential addition to your collection.

This new edition of the successful Staged Diabetes Management will again address the prominent issues of primary care diabetes management based on the International Diabetes Center’s “Staged Diabetes Management” program, which it advocates as part of its mission statement. This systematic treatment program consists of practical solutions to the detection and treatment of diabetes, its complications, and such areas as metabolic syndrome, pre-diabete,s and diabetes in children using evidence-based medicine. The text reviews the fundamental basis of diabetes management and then addresses treatment of each type of diabetes and the major micro- and macrovascular complications.

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.

A well-balanced overview of mathematical approaches to complex systems ranging from applications in chemistry and ecology to basic research questions on network complexity. Matthias Dehmer, Abbe Mowshowitz, and Frank Emmert-Streib, well-known pioneers in the fi eld, have edited this volume with a view to balancing classical and modern approaches to ensure broad coverage of contemporary research problems. The book is a valuable addition to the literature and a must-have for anyone dealing with network compleaity and complexity issues.

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologies for bioisostere identification and replacement: physicochemical properties, topology, shape, and overlays of protein-ligand crystal structures. In the final part, several real-world examples of bioisosterism in drug discovery projects are discussed. With its detailed descriptions of databases, methods and real-life case studies, this is tailor-made for busy industrial researchers with little time for reading, while remaining easily accessible to novice drug developers due to its systematic structure and introductory section.

The Atlas of Endoscopic Ultrasonography provides readers with a large collection of excellent images obtained from both diagnostic and therapeutic procedures. The Atlas includes a DVD which will be an invaluable addition to the library of trainee and practising gastroenterologists with video clips and searchable database of images. Together the book and DVD offer a first class collection of images to give a highly integrated introduction to endoscopic ultrasonography. The Atlas is an ideal companion to Dr Gress et al’s Endoscopic Ultrasonography, Second Edition.

The ABC of Kidney Disease is a brand new title in the successful ABC series which explains this complicated area thoroughly and clearly, in a practical and user-friendly manner. Providing information on a wide variety of renal diseases, this book ensures non-renal healthcare workers are able to screen, identify, treat and refer renal patients appropriately. Covering signs, symptoms, treatments and causes of renal disease, this title includes the common issues presenting to GPs, what tests to use, how to interpret results and when to refer a patient to a kidney specialist. The ABC of Kidney Disease is an ideal practical reference for GPs, GP registrars and junior doctors.

Electrocardiography is an essential tool in diagnosing cardiac disorders. This second edition of the ABC of Clinical Electrocardiography allows readers to become familiar with the wide range of patterns seen in the electrocardiogram in clinical practice and covers the fundamentals of ECG interpretation and analysis. Fully revised and updated, this edition includes a self-assessment section to aid revision and check comprehension, clear anatomical diagrams to illustrate key points and a larger format to show 12-lead ECGs clearly and without truncation. Edited and written by leading experts, the ABC of Clinical Electrocardiography is a valuable text for anyone managing patients with heart disorders, both in general practice and in hospitals. Junior doctors and nurses, especially those working in cardiology and emergency departments, as well as medical students, will find this a vaulable introduction to the understanding of this key clinical tool.

Clinical Sedation in Dentistry is a comprehensive textbook on the principles and practice of clinical sedation in dentistry, written by experienced educators and internationally renowned researchers in the field. Chapters cover the following key topics: the aetiology of dental anxiety, patient management techniques, anatomy and physiology, pharmacology, patient assessment and selection, inhalation and intravenous sedation, pre-medication and oral sedation, sedation and special care dentistry, complications and emergencies, medico-legal aspects and recent advances. This textbook is aimed primarily at undergraduate dental students, dental care professionals and postgraduate dentists.

Jones' Clinical Paediatric Surgery provides clear-sighted advice on the surgical options available for young patients. Building on the popular and successful style of previous editions, this fully revised seventh edition employs a systematic approach to the childhood diseases that need surgical treatment. It includes more case vignettes and colour photographs, expanded coverage on the use of imaging, and updated approaches to management including laparoscopic operations. Key subject areas are supported by case vignettes in a familiar format similar to what might appear in an OSCE viva. Jones' Clinical Paediatric Surgery is the ideal guide for paeditricians, surgeons and trainees, as well as primary care physicians, junior doctors and medical students.